Evidence map›Paper›PMID 32098431›Full record

ArticleJournal of functional biomaterials2020

Printing 3D Hydrogel Structures Employing Low-Cost Stereolithography Technology.

Leila Samara S M Magalhães, Francisco Eroni Paz Santos, Conceição de Maria Vaz Elias, Samson Afewerki, Gustavo F Sousa, Andre S A Furtado, Fernanda Roberta Marciano, Anderson Oliveira Lobo

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Enhanced bone regeneration via local low-dose delivery of PTHFrontiers in bioengineering and biotechnology · 2023
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Advances in 3D Printing for Tissue Engineering.Materials (Basel, Switzerland) · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Leila Samara S M MagalhãesLIMAV - Interdisciplinary Laboratory for Advanced Materials, BioMatLab, Materials Science and Engineering Graduate Program, UFPI - Federal University of Piauí, Teresina 64049-550, Brazil.
Francisco Eroni Paz SantosLIMAV - Interdisciplinary Laboratory for Advanced Materials, BioMatLab, Materials Science and Engineering Graduate Program, UFPI - Federal University of Piauí, Teresina 64049-550, Brazil.
Conceição de Maria Vaz EliasBiomedical Engineering Graduate Program, University of Brazil, São Paulo 08230-030, Brazil.
Samson AfewerkiDivision of Engineering in Medicine, Department of Medicine, Harvard Medical School, Brigham & Women´s Hospital, Cambridge, MA 02139, USA.
Gustavo F SousaLIMAV - Interdisciplinary Laboratory for Advanced Materials, BioMatLab, Materials Science and Engineering Graduate Program, UFPI - Federal University of Piauí, Teresina 64049-550, Brazil.
Andre S A FurtadoLIMAV - Interdisciplinary Laboratory for Advanced Materials, BioMatLab, Materials Science and Engineering Graduate Program, UFPI - Federal University of Piauí, Teresina 64049-550, Brazil.
Fernanda Roberta MarcianoDepartment of Physics, UFPI - Federal University of Piauí, Teresina 64049-550, Brazil.
Anderson Oliveira LoboLIMAV - Interdisciplinary Laboratory for Advanced Materials, BioMatLab, Materials Science and Engineering Graduate Program, UFPI - Federal University of Piauí, Teresina 64049-550, Brazil.
Universidade Federal do Piauí · BRBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereolithography technology associated with the employment of photocrosslinkable, biocompatible, and bioactive hydrogels have been widely used. This method enables 3D microfabrication from images created by computer programs and allows researchers to design various complex models for tissue engineering applications. This study presents a simple and fast home-made stereolithography system developed to print layer-by-layer structures. Polyethylene glycol diacrylate (PEGDA) and gelatin methacryloyl (GelMA) hydrogels were employed as the photocrosslinkable polymers in various concentrations. Three-dimensional (3D) constructions were obtained by using the stereolithography technique assembled from a commercial projector, which emphasizes the low cost and efficiency of the technique. Lithium phenyl-2,4,6-trimethylbenzoyl phosphonate (LAP) was used as a photoinitiator, and a 404 nm laser source was used to promote the crosslinking. Three-dimensional and vascularized structures with more than 5 layers and resolutions between 42 and 83 µm were printed. The 3D printed complex structures highlight the potential of this low-cost stereolithography technique as a great tool in tissue engineering studies, as an alternative to bioprint miniaturized models, simulate vital and pathological functions, and even for analyzing the actions of drugs in the human body.

Indexed as

3D printingbioprintingGelMAhydrogelsPEGDA.stereolithography

Identifiers

PMID32098431
PMCPMC7151634
OpenAlexW3008005887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.