Evidence map›Paper›PMID 32098311›Full record

ReviewGenes2020

Hearing Impairment Overview in Africa: the Case of Cameroon.

Edmond Wonkam Tingang, Jean Jacques Noubiap, Jean Valentin F Fokouo, Oluwafemi Gabriel Oluwole, Séraphin Nguefack, Emile R Chimusa, Ambroise Wonkam

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. In pursuit of increasing the application of tele-audiology in South Africa: COVID-19 puts on the alert for patient site facilitator training.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2022
    Pooled it
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  15. A novel variant inExperimental biology and medicine (Maywood, N.J.) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Edmond Wonkam TingangDivision of Human Genetics, Department of Pathology, University of Cape Town, Cape Town 7925, South Africa.
Jean Jacques NoubiapCentre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and Royal Adelaide Hospital, Adelaide 5000, Australia.
Jean Valentin F FokouoENT unit, Bertoua Regional Hospital, P.O. Box 40, Bertoua, Cameroon.
Oluwafemi Gabriel OluwoleDivision of Human Genetics, Department of Pathology, University of Cape Town, Cape Town 7925, South Africa.ORCID 0000-0003-2010-1709
Séraphin NguefackDepartment of Paediatrics, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé 1364, Cameroon.
Emile R ChimusaDivision of Human Genetics, Department of Pathology, University of Cape Town, Cape Town 7925, South Africa.ORCID 0000-0001-8846-2047
Ambroise WonkamDivision of Human Genetics, Department of Pathology, University of Cape Town, Cape Town 7925, South Africa.ORCID 0000-0003-1420-9051
University of Cape Town · ZARoyal Adelaide Hospital · AUUniversité de Yaoundé I · CM

Funding

Sickle Africa Data Coordinating CenterU24HL135600 · NHLBI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA, WONKAM, AMBROISE · 2017 to 2025
$8.6M
Hearing Impairment Genetics Studies in Africa (HI-GENES Africa)U01HG009716 · NHGRI · UNIVERSITY OF CAPE TOWN · PI WONKAM, AMBROISE · 2017 to 2021
$1.2M
NHGRI NIH HHS U01 HG009716NHLBI NIH HHS U24 HL135600Wellcome Trust H3A/18/001
6 · The paper itself

Abstract

The incidence of hearing impairment (HI) is higher in low- and middle-income countries when compared to high-income countries. There is therefore a necessity to estimate the burden of this condition in developing world. The aim of our study was to use a systematic approach to provide summarized data on the prevalence, etiologies, clinical patterns and genetics of HI in Cameroon. We searched PubMed, Scopus, African Journals Online, AFROLIB and African Index Medicus to identify relevant studies on HI in Cameroon, published from inception to 31 October, 2019, with no language restrictions. Reference lists of included studies were also scrutinized, and data were summarized narratively. This study is registered with PROSPERO, number CRD42019142788. We screened 333 records, of which 17 studies were finally included in the review. The prevalence of HI in Cameroon ranges from 0.9% to 3.6% in population-based studies and increases with age. Environmental factors contribute to 52.6% to 62.2% of HI cases, with meningitis, impacted wax and age-related disorder being the most common ones. Hereditary HI comprises 0.8% to 14.8% of all cases. In 32.6% to 37% of HI cases, the origin remains unknown. Non-syndromic hearing impairment (NSHI) is the most frequent clinical entity and accounts for 86.1% to 92.5% of cases of HI of genetic origin. Waardenburg and Usher syndromes account for 50% to 57.14% and 8.9% to 42.9% of genetic syndromic cases, respectively. No pathogenic mutation was described in

Indexed as

AfricaCameroonConnexinsDeafnessGenotypeHearing LossHearing Loss, SensorineuralHumansIncidenceMutationPrevalenceConnexinsAfricaCameroonetiologiesgeneticshearing impairmentprevalence

Identifiers

PMID32098311
PMCPMC7073999
OpenAlexW3008310179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.