Evidence map›Paper›PMID 32098194›Full record

ArticleCancers2020

Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells.

Rubén A Bartolomé, Ángela Martín-Regalado, Marta Jaén, Markella Zannikou, Peng Zhang, Vivian de Los Ríos, Irina V Balyasnikova, J Ignacio Casal

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

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  19. Protein Tyrosine Phosphatases: Mechanisms in Cancer.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rubén A BartoloméDepartment of Molecular Biomedicine, Centro de Investigaciones Biológicas, CSIC. Ramiro de Maeztu 9, 28039 Madrid, Spain.
Ángela Martín-RegaladoDepartment of Molecular Biomedicine, Centro de Investigaciones Biológicas, CSIC. Ramiro de Maeztu 9, 28039 Madrid, Spain.
Marta JaénDepartment of Molecular Biomedicine, Centro de Investigaciones Biológicas, CSIC. Ramiro de Maeztu 9, 28039 Madrid, Spain.
Markella ZannikouDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Peng ZhangDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Vivian de Los RíosProteomics Core facility, Centro de Investigaciones Biológicas (CSIC), 28001 Madrid, Spain.
Irina V BalyasnikovaDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
J Ignacio CasalDepartment of Molecular Biomedicine, Centro de Investigaciones Biológicas, CSIC. Ramiro de Maeztu 9, 28039 Madrid, Spain.
Centro de Investigaciones Biológicas Margarita Salas · ESNorthwestern University · US

Funding

Genetic Approaches to Optimize CAR T cells for Glioblastoma TherapyR01NS106379 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BALYASNIKOVA, IRINA V, GOTTSCHALK, STEPHEN · 2018 to 2022
$2.7M
Intranasal Stem-Cell Based Therapy for GlioblastomaR01NS087990 · NINDS · UNIVERSITY OF CHICAGO · PI BALYASNIKOVA, IRINA V · 2014 to 2018
$2.1M
Neural Stem Cell Carriers for Glioblastoma ImmunotherapyR21NS101150 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BALYASNIKOVA, IRINA V · 2017 to 2018
$775k
Foundation for the National Institutes of Health R21NS101150, R01NS106379, and R01NS087990Instituto de Salud Carlos III PRB3 (ISCIII-SGEFI/FEDER- PT17/0019/0008)Ministerio de Economía, Industria y Competitividad, Gobierno de España BIO2015-66489-R, RTI2018-095055-B100NINDS NIH HHS R01 NS087990NINDS NIH HHS R01 NS106379NINDS NIH HHS R21 NS101150
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

colorectal cancerEGFRglioblastomaIL13Rα2metastasisovarian cancerPTP1BSrc

Identifiers

PMID32098194
PMCPMC7072372
OpenAlexW3007479674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.