ReviewJournal of clinical medicine2020
Sleep Apnea, Hypertension and the Sympathetic Nervous System in the Adult Population.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05438446 (Effect of Renal Denervation on Stress, Hypertension and Anxiety Management), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Renal Denervation on Stress, Hypertension and Anxiety Management (ERSHAM Study) in Patients With Uncontrolled Hypertension
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Effects of continuous positive airway pressure therapy on glucose metabolism in patients with obstructive sleep apnoea and type 2 diabetes: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness.American journal of respiratory and critical care medicine · 2022Trial
- D-dimer in Marfan syndrome: effect of obstructive sleep apnea induced blood pressure surges.American journal of physiology. Heart and circulatory physiology · 2022Trial
- Pleiotropic effects of renal denervation beyond blood pressure reduction.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Association between high likelihood of obstructive sleep apnea and masked hypertension: findings from the Jackson heart and coronary artery risk development in young adults studies.Journal of hypertension · 2026Article
- Chronicity and comorbidities: Is estimated longer duration of obstructive sleep apnoea linked to higher cardiometabolic risk?Lung India : official organ of Indian Chest Society · 2026Article
- Obstructive Sleep Apnea and Recovery in Athletes: BMI and Neck Circumference and Their Impact on Recovery Capacity and Injury Risk.Life (Basel, Switzerland) · 2026Review
- Mediating Effect of Serum Uric Acid in the Association Between Nocturia and Mortality.International neurourology journal · 2025Article
- Association between sleep duration and estimated glomerular filtration rate in Chinese patients with diabetes: evidence from a cross-sectional study.European journal of medical research · 2025Observational
- Comparative effects of MAD and CPAP on heart rate in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2025Observational
- Abnormalities in the genioglossus muscle and its neuromuscular synapse in leptin-deficient male mice.Skeletal muscle · 2025Article
- A Predictive Model and Scoring System for All-Cause Mortality in Patients With Atrial Fibrillation Combined With Obstructive Sleep Apnea Syndrome: A Retrospective Case-Control Study.Reviews in cardiovascular medicine · 2025Article
- Article
- Resistant Hypertension: A Brief Review of Pathophysiology.Journal of general internal medicine · 2025Review
- Correlation between TG/HDL-C ratio and obstructive sleep apnea in the adult US population: a cross-sectional study.Frontiers in neurology · 2025Article
- Association between dietary nutrient intake and sleep disorders in hypertensive patients: a cross-sectional study of NHANES, 2005-2020.Frontiers in nutrition · 2025Article
- Renal nerves in physiology, pathophysiology and interoception.Nature reviews. Nephrology · 2025Review
- One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study.Journal of clinical medicine · 2024Article
- Remote Monitoring of Sympathovagal Imbalance During Sleep and Its Implications in Cardiovascular Risk Assessment: A Systematic Review.Bioengineering (Basel, Switzerland) · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Sleep apnea is very common in patients with cardiovascular disease, especially in patients with hypertension. Over the last few decades a number of discoveries have helped support a causal relationship between the two and even resistant hypertension. The role neurogenic mechanisms play has gathered more attention in the recent past due to their immediate bedside utility. Several innovative discoveries in pathogenesis including those exploring the role of baroreflex gain, cardiovascular variability, chemoreceptor reflex activation and the sympathetic nervous system have emerged. In this review, we discuss the epidemiology of sleep apnea and hypertension and the pathogenic mechanisms contributing to neurogenic hypertension. Furthermore, recent management strategies in addition to continuous positive airway pressure (CPAP), such as upper airway stimulation and renal denervation that target these pathogenic mechanisms, are also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.