Evidence map›Paper›PMID 32098061›Full record

ArticleInternational journal of molecular sciences2020

Biapenem as a Novel Insight into Drug Repositioning against Particulate Matter-Induced Lung Injury.

Wonhwa Lee, Moon-Chang Baek, Kyung-Min Kim, Jong-Sup Bae

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Air pollution-induced airway epithelial barrier dysfunction in COPD: a narrative review of mechanisms and therapeutic implications.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wonhwa LeeCollege of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, BK21 Plus KNU Multi-Omics based Creative Drug Research Team, Kyungpook National University, Daegu 41566, Korea.
Moon-Chang BaekDepartment of Molecular Medicine, CMRI, School of Medicine, Kyungpook National University, Daegu 41566, Korea.
Kyung-Min KimDivision of Plant Biosciences, School of Applied BioSciences, College of Agriculture and Life Science, Kyungpook National University, Daegu 41566, Korea.ORCID 0000-0003-4812-6297
Jong-Sup BaeCollege of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, BK21 Plus KNU Multi-Omics based Creative Drug Research Team, Kyungpook National University, Daegu 41566, Korea.ORCID 0000-0002-5756-9367
Kyungpook National University · KR

Funding

a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea HI15C0001by the National Research Foundation of Korea (NRF) grant funded by the Korean government 2017M3A9G8083382
6 · The paper itself

Abstract

The screening of biologically active chemical compound libraries can be an efficient way to reposition Food and Drug Adminstration (FDA)-approved drugs or to discover new therapies for human diseases. Particulate matter with an aerodynamic diameter equal to or less than 2.5 μm (PM

Indexed as

Drug RepositioningLungLung InjuryAnimalsBeclin-1Bronchoalveolar LavageCytokinesLymphocytesMaleMiceMice, Inbred BALB CMicrotubule-Associated ProteinsMyeloid Differentiation Factor 88Particulate MatterThienamycinsToll-Like Receptor 4Beclin-1Becn1 protein, mousebiapenemCytokinesMap1lc3b protein, mouseMicrotubule-Associated ProteinsmTOR protein, mouseMyd88 protein, mouseMyeloid Differentiation Factor 88Particulate MatterThienamycinsTlr4 protein, mouseToll-Like Receptor 4TOR Serine-Threonine Kinasesbiapenemdrug repositioninglung injuryparticulate matterTLR4-mTOR-autophagy

Identifiers

PMID32098061
PMCPMC7073049
OpenAlexW3007487951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.