Evidence map›Paper›PMID 32097518›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Synthesis of Small-Molecule Fluorescent Probes for the In Vitro Imaging of Calcium-Activated Potassium Channel K

Kathrin Brömmel, Sarah Maskri, Ivan Maisuls, Christian Paul Konken, Marius Rieke, Zoltan Pethő, Cristian A Strassert, Oliver Koch, Albrecht Schwab, Bernhard Wünsch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Visualization of KACS pharmacology & translational science · 2025
    Article
  2. Article
  3. Review
  4. Imaging of KChemMedChem · 2023
    Article
  5. Review
  6. Article
  7. Recent Progress on Synthesis ofMolecules (Basel, Switzerland) · 2021
    Review
  8. Co-staining of KChemMedChem · 2020
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kathrin BrömmelInstitute for Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms-University Münster, Corrensstraße 48, 48149, Münster, Germany.
Sarah MaskriInstitute for Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms-University Münster, Corrensstraße 48, 48149, Münster, Germany.
Ivan MaisulsCenter for Nanotechnology, Center for Soft Nanoscience, Institute for Inorganic and Analytical Chemistry, Westphalian Wilhelms-University Münster, Heisenbergstraße 11, 48149, Münster, Germany.
Christian Paul KonkenDepartment of Nuclear Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, 48149, Münster, Germany.
Marius RiekeInstitute for Physiology II, University Hospital Münster, Robert-Koch-Straße 27b, 48149, Münster, Germany.
Zoltan PethőInstitute for Physiology II, University Hospital Münster, Robert-Koch-Straße 27b, 48149, Münster, Germany.
Cristian A StrassertCenter for Nanotechnology, Center for Soft Nanoscience, Institute for Inorganic and Analytical Chemistry, Westphalian Wilhelms-University Münster, Heisenbergstraße 11, 48149, Münster, Germany.
Oliver KochInstitute for Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms-University Münster, Corrensstraße 48, 48149, Münster, Germany.
Albrecht SchwabInstitute for Physiology II, University Hospital Münster, Robert-Koch-Straße 27b, 48149, Münster, Germany.
Bernhard WünschInstitute for Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms-University Münster, Corrensstraße 48, 48149, Münster, Germany.ORCID 0000-0002-9030-8417

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small-molecule probes for the in vitro imaging of K

Indexed as

A549 CellsBinding SitesBoron CompoundsCycloaddition ReactionFluorescent DyesHumansIntermediate-Conductance Calcium-Activated Potassium ChannelsLigandsMicroscopy, FluorescenceMolecular Dynamics Simulation4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsFluorescent DyesIntermediate-Conductance Calcium-Activated Potassium ChannelsKCNN4 protein, humanLigandscycloadditionfluorescent probesKCa3.1 channelsmolecular modellingnon-small cell lung cancer

Identifiers

PMID32097518
PMCPMC7318252

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.