Evidence map›Paper›PMID 32097326›Full record

ArticlePlastic and reconstructive surgery2020

Opioid Prescribing and Use Patterns in Postsurgical Facial Trauma Patients.

Jodi B Lapidus, Katherine B Santosa, Gary B Skolnick, Avira Som, Gerald J Cho, Jennifer F Waljee, Jacob D AuBuchon, Kamlesh B Patel

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Plastic and reconstructive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06429501 (The Impact of Perioperative Nerve Block on Opioid Use After Craniomaxillofacial Trauma Surgery), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06429501 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

The Impact of Perioperative Nerve Block on Opioid Use After Craniomaxillofacial Trauma Surgery: A Randomized Controlled Trial

TypeinterventionalSponsorWashington University School of MedicineRan2024 to 2027Enrolled70ConditionsPain ManagementArmsBupivacaine/Epinephrine, Saline
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Opioid Dependency After Craniomaxillofacial Trauma Surgery.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  2. Review
  3. Opioid consumption after lower limb amputation in Medicare beneficiaries.PM & R : the journal of injury, function, and rehabilitation · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jodi B LapidusFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
Katherine B SantosaFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
Gary B SkolnickFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
Avira SomFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
Gerald J ChoFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
Jennifer F WaljeeFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
Jacob D AuBuchonFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
Kamlesh B PatelFrom the Division of Plastic Surgery, Department of Surgery, and the Department of Anesthesiology, Washington University School of Medicine; and the Section of Plastic Surgery, Department of Surgery, University of Michigan.
University of Washington · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
WASHINGTON UNIVERSITY CER MENTORED CAREER DEVELOPMENT AWARD KM1KM1CA156708 · NCI · WASHINGTON UNIVERSITY · PI FRASER, VICTORIA J. · 2010 to 2010
$2.5M
WASHINGTON UNIVERSITY COMPARATIVE EFFECTIVENESS ADMINISTRATIVE DATA REPOSITORYR24HS019455 · AHRQ · WASHINGTON UNIVERSITY · PI FRASER, VICTORIA J. · 2010 to 2010
$969k
Molecular Mechanisms of Terminal Schwann Cell Response After Nerve InjuryF32NS098561 · NINDS · WASHINGTON UNIVERSITY · PI SANTOSA, KATHERINE BERNADETTE · 2016 to 2017
$123k
AHRQ HHS R24 HS019455NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS KM1 CA156708NINDS NIH HHS F32 NS098561
6 · The paper itself

Abstract

backgroundFacial fractures are painful injuries routinely managed by opioids after surgical repair. Studies have identified patient risk factors and prescribing patterns associated with opioid use in medicine and general surgery; however, little is known about these entities in the facial trauma population.

methodsA retrospective cohort study of opioid-naive patients undergoing surgical repair of facial fractures was conducted using the Truven Health MarketScan Commercial Claims and Encounters (2006 to 2015) and Medicaid Multi-State Databases (2011 to 2015). Eligible procedures included nasal, nasoorbitoethmoid, orbital, mandible, and Le Fort fracture repair. Opioid type, daily dosage, and prescription duration were analyzed. Multivariable logistic regression was performed to determine independent predictors of prescription refill.

resultsA total of 20,191 patients undergoing surgical repair of facial fractures were identified. Of these, 15,861 patients (78.6 percent) filled a perioperative opioid prescription. Refill (58.7 percent) and potentially inappropriate prescribing (39.4 percent) were common among this population. Patient factors including prior substance use (adjusted OR, 1.84; 95 percent CI, 1.63 to 2.07) and history of mental health disorder (adjusted OR, 1.43; 95 percent CI, 1.06 to 1.91) were independent predictors of refill. Increased odds of refill were seen in patients prescribed tramadol (OR, 1.98; 95 percent CI, 1.48 to 2.66) and those who underwent multiple surgical repairs (OR, 3.38; 95 percent CI, 2.54 to 4.50).

conclusionsRefill and potentially inappropriate prescribing occurred at high rates in facial trauma patients undergoing surgical repair. Additional studies are needed to develop guidelines for proper opioid prescribing in this population. CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, III.

Indexed as

AdolescentAdultAnalgesics, OpioidDrug PrescriptionsFacial BonesFemaleFracture FixationHumansInappropriate PrescribingMaleMiddle AgedOpioid EpidemicOpioid-Related DisordersPostoperative PainPostoperative PeriodPractice Patterns, Physicians'Analgesics, OpioidTramadol

Identifiers

PMID32097326
PMCPMC7080326
OpenAlexW3006869089

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.