ArticleJournal of addiction medicine2020
Historical Perspective of Proactive and Reactive Regulations of E-cigarettes to Combat Nicotine Addiction.
Article in Journal of addiction medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Biological aging acceleration associated with electronic cigarette use in the United States.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Electronic Cigarette Use (Vaping) Among Adolescents: A Narrative Review of an Emerging Public Health Epidemic.Cureus · 2025Review
- Exclusive and dual use of electronic cigarettes among European youth in 32 countries with different regulatory landscapes.Tobacco control · 2024Article
- Effects of Device Settings and E-Liquid Characteristics on Mouth-Throat Losses of Nicotine Delivered with Electronic Nicotine Delivery Systems (ENDS).Journal of aerosol science · 2023Article
- E-Liquids from Seven European Countries-Warnings Analysis and Freebase Nicotine Content.Toxics · 2022Article
- La protection des enfants et des adolescents contre les risques du vapotage.Paediatrics & child health · 2021Review
- Protecting children and adolescents against the risks of vaping.Paediatrics & child health · 2021Review
- Potential factors affecting free base nicotine yield in electronic cigarette aerosols.Expert opinion on drug delivery · 2021Article
- Machine Learning-Based Nicotine Addiction Prediction Models for Youth E-Cigarette and Waterpipe (Hookah) Users.Journal of clinical medicine · 2021Article
- Nicotine forms: why and how do they matter in nicotine delivery from electronic cigarettes?Expert opinion on drug delivery · 2020Review
- Vaping ΔExpert review of clinical pharmacologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Cigarettes and electronic cigarettes (e-cigarettes) are major sources of exposure to nicotine, an addictive chemical. Although these products are being regulated by the Food and Drug Administration (FDA) under the Tobacco Control Act, specifications about the nicotine content in these products have not been established yet. In e-cigarettes, nicotine concentration ranges from 0 to > 50mg/mL, and the recent e-cigarette devices provide control to change nicotine flux for higher nicotine delivery. Due to the lack of robust regulations in manufacturing, distribution and marketing, e-cigarettes have already infiltrated the market with youth appealing flavors and devices. As a result, the country is facing a youth epidemic of e-cigarette use. The unregulated nicotine levels in both cigarettes and e-cigarettes can lead to repeated and overexposure of nicotine to youth which can lead to the addiction and detrimental effects on their cognitive functions. Over the past decade, the corrective measures being taken by the FDA for cigarette and e-cigarette regulations also should focus on nicotine exposure levels. Before it is too late to prevent youth from lifetime addiction to nicotine, it is important to address the issues of nicotine concentration, nicotine flux and the e-cigarette device regulations while offering adults with smoking disorder less harmful alternatives to cigarettes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.