Evidence map›Paper›PMID 32096998›Full record

ArticleJournal of natural products2020

Na

Yulin Ren, Hennrique T Ribas, Kimberly Heath, Sijin Wu, Jinhong Ren, Pratik Shriwas, Xiaozhuo Chen, Michael E Johnson, Xiaolin Cheng, Joanna E Burdette and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of natural products, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. NaFrontiers in chemistry · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Cytotoxic and Noncytotoxic Steroidal Constituents ofJournal of natural products · 2025
    Article
  6. Digoxin and its NaBioorganic & medicinal chemistry · 2024
    Review
  7. Article
  8. Article
  9. Bioactive C21 Steroidal Glycosides fromMolecules (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Cardiac glycosides fromRSC advances · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Toxins · 2021
    Review
  18. Review
  19. NaMolecules (Basel, Switzerland) · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yulin RenDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Hennrique T RibasDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Kimberly HeathDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Sijin WuDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.
Jinhong RenCenter for Biomolecular Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Pratik Shriwas
Xiaozhuo Chen
Michael E JohnsonDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Xiaolin ChengDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.ORCID 0000-0002-7396-3225
Joanna E BurdetteDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-7271-6847
A Douglas KinghornDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States.ORCID 0000-0002-6647-8707
The Ohio State University · USUniversity of Illinois Chicago · USBiotechnology Institute · US

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI JIMMY ORJALA · 2007 to 2026
$27.2M
NCI NIH HHS P01 CA125066
6 · The paper itself

Abstract

(+)-Digoxin (

Indexed as

Antineoplastic AgentsCardenolidesCell Line, TumorDigoxinHumansMolecular Docking SimulationMolecular StructureSodium-Potassium-Exchanging ATPaseStructure-Activity RelationshipAntineoplastic AgentsCardenolidesDigoxinSodium-Potassium-Exchanging ATPase

Identifiers

PMID32096998
PMCPMC7243443
OpenAlexW3009016612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.