Evidence map›Paper›PMID 32096757›Full record

ArticleDevelopment and psychopathology2021

Parents still matter! Parental warmth predicts adolescent brain function and anxiety and depressive symptoms 2 years later.

Rosalind D Butterfield, Jennifer S Silk, Kyung Hwa Lee, Greg S Siegle, Ronald E Dahl, Erika E Forbes, Neal D Ryan, Jill M Hooley, Cecile D Ladouceur

Open access · greenAbstract read
In one paragraph

Article in Development and psychopathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 119 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Rosalind D ButterfieldDepartment of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-2310-2432
Jennifer S SilkDepartment of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.
Kyung Hwa LeeDivision of Child and Adolescent Psychiatry, Seoul National University Hospital, Seoul, South Korea.
Greg S SiegleDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Ronald E DahlSchool of Public Health, University of California-Berkeley, Berkeley, CA, USA.
Erika E ForbesDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Neal D RyanDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Jill M HooleyDepartment of Psychology, Harvard University, Cambridge, MA, USA.
Cecile D LadouceurDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USHarvard University · USSeoul National University Hospital · KRUniversity of California, Berkeley · US

Funding

Transdisciplinary Studies of CBT for Anxiety in YouthP50MH080215 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI IYENGAR, SATISH · 2008 to 2012
$9.5M
Puberty and Threat/Reward Processing in the Trajectory from Anxiety to DepressionR01MH091327 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SILK, JENNIFER S · 2010 to 2014
$3.4M
NIMH NIH HHS P50 MH080215NIMH NIH HHS R01 MH091327
6 · The paper itself

Abstract

Anxiety is the most prevalent psychological disorder among youth, and even following treatment, it confers risk for anxiety relapse and the development of depression. Anxiety disorders are associated with heightened response to negative affective stimuli in the brain networks that underlie emotion processing. One factor that can attenuate the symptoms of anxiety and depression in high-risk youth is parental warmth. The current study investigates whether parental warmth helps to protect against future anxiety and depressive symptoms in adolescents with histories of anxiety and whether neural functioning in the brain regions that are implicated in emotion processing and regulation can account for this link. Following treatment for anxiety disorder (Time 1), 30 adolescents (M age = 11.58, SD = 1.26) reported on maternal warmth, and 2 years later (Time 2) they participated in a functional neuroimaging task where they listened to prerecorded criticism and neutral statements from a parent. Higher maternal warmth predicted lower neural activation during criticism, compared with the response during neutral statements, in the left amygdala, bilateral insula, subgenual anterior cingulate (sgACC), right ventrolateral prefrontal cortex, and anterior cingulate cortex. Maternal warmth was associated with adolescents' anxiety and depressive symptoms due to the indirect effects of sgACC activation, suggesting that parenting may attenuate risk for internalizing through its effects on brain function.

Indexed as

DepressionMagnetic Resonance ImagingAdolescentAnxietyAnxiety DisordersBrainChildHumansParentsadolescenceanxietydepressionfMRIparental warmth

Identifiers

PMID32096757
PMCPMC7483163
OpenAlexW3007047023

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.