Evidence map›Paper›PMID 32096320›Full record

ArticleTraffic (Copenhagen, Denmark)2020

Components of the G

Alexey Bondar, Wonjo Jang, Ekaterina Sviridova, Nevin A Lambert

Open access · bronzeAbstract read
In one paragraph

Article in Traffic (Copenhagen, Denmark), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Local GPCR density tips the balance of μ-opioid receptor trafficking.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Class A and B GPCRs trigger rapid GαCommunications biology · 2025
    Article
  4. Serotonin 5-HTMolecular biology of the cell · 2023
    Article
  5. BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated GProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Alexey BondarDepartment of Pharmacology and Toxicology, Augusta University, Augusta, Georgia, USA.ORCID 0000-0002-1980-2930
Wonjo JangDepartment of Pharmacology and Toxicology, Augusta University, Augusta, Georgia, USA.
Ekaterina SviridovaCenter for Nanobiology and Structural Biology, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Czech Republic.
Nevin A LambertDepartment of Pharmacology and Toxicology, Augusta University, Augusta, Georgia, USA.ORCID 0000-0001-7550-0921
Augusta University · USCzech Academy of Sciences · CZSewanee: The University of the South · US

Funding

Direct assessment of GPCR-transducer coupling and G protein subtype biasR01GM130142 · NIGMS · AUGUSTA UNIVERSITY · PI LAMBERT, NEVIN ALAN · 2018 to 2021
$1.5M
Grantová Agentura České Republiky 20-09628YGrantová Agentura České Republiky 20-11563YGrantová Agentura České Republiky P303/17-14413YNIGMS NIH HHS R01 GM130142NIH HHS GM130142
6 · The paper itself

Abstract

The G protein signaling cascade is a key player in cell signaling. Cascade activation leads to a redistribution of its members in various cellular compartments. These changes are likely related to the "second wave" of signaling from endosomes. Here, we set out to determine whether G

Indexed as

Signal TransductionCaveolaeCell MembraneGTP-Binding ProteinsReceptors, Adrenergic, beta-2GTP-Binding ProteinsReceptors, Adrenergic, beta-2adenylyl cyclaseadrenergic receptorarrestincaveolinclathrinG protein-coupled receptorGs protein

Identifiers

PMID32096320
PMCPMC7333016
OpenAlexW3006681006

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.