Evidence map›Paper›PMID 32096249›Full record

ArticleScandinavian journal of medicine & science in sports2020

Patellofemoral alignment and geometry and early signs of osteoarthritis are associated in patellofemoral pain population.

Joost F A Eijkenboom, Rianne A van der Heijden, Janneke L M de Kanter, Edwin H Oei, Sita M A Bierma-Zeinstra, Marienke van Middelkoop

Open access · hybridAbstract read
In one paragraph

Article in Scandinavian journal of medicine & science in sports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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  4. Effects of TJournal of magnetic resonance imaging : JMRI · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joost F A EijkenboomDepartment of General Practice, Erasmus MC University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-8058-5448
Rianne A van der HeijdenDepartment of Radiology & Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Janneke L M de KanterDepartment of Radiology & Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Edwin H OeiDepartment of Radiology & Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Sita M A Bierma-ZeinstraDepartment of General Practice, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Marienke van MiddelkoopDepartment of General Practice, Erasmus MC University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-6926-0618
Erasmus MC · NL

Funding

Dutch Arthritis FoundationErasmus University RotterdamStichting Anna Fonds | NOREF
6 · The paper itself

Abstract

backgroundPatellofemoral pain (PFP) patients show increased prevalence of patellar malalignment. Structural and alignment abnormalities of the patellofemoral joint (PFJ) may play a role in development of PFP and patellofemoral osteoarthritis (PFOA).

objectivesEvaluating associations of patellofemoral alignment and femoral geometry with bony and cartilaginous abnormalities in PFP patients and healthy control subjects.

methodsData from a case-control study were used (64 PFP subjects, 70 control subjects, 57% female, age 23.2 (6.4)). Alignment and femoral geometry measures in the PFJ were determined using MRI. Structural abnormalities in the PFJ associated with OA (bone marrow lesions, osteophytes, minor cartilage defects and Hoffa-synovitis), quantified cartilage composition (T1ρ relaxation times) in the PFJ and perfusion within the patellar bone were examined using different MRI techniques. Associations were analyzed using regression analyses, adjusted for potential confounders.

resultsLateral patellar tilt was negatively associated with presence of osteophytes on both patella (OR 0.91; 95% CI 0.84 to 0.98), anterior femur (OR 0.92; 95% CI 0.84 to 0.99) and minor cartilage defects on patella (OR 0.91; 95% CI 0.84 to 0.99). Patella alta was positively associated with the presence of bone marrow lesions in the patella and minor cartilage defects (OR 48.33; 95% CI 4.27 to 547.30 and OR 17.51; 95% CI 1.17 to 262.57, respectively). Patella alta and medial patellar translation were positively associated with T1ρ relaxation times within trochlear cartilage (β 5.2; 95% CI 0.77 to 9.58, and 0.36; 95% CI 0.08 to 0.64, respectively). None of the alignment and geometry measures were associated with bone perfusion.

conclusionOur study implies that associations between patellofemoral alignment and geometry and structural joint abnormalities linked to OA are already present in both PFP patients and healthy control subjects.

Indexed as

AdolescentAdultArthralgiaCase-Control StudiesFemaleFemurHumansMagnetic Resonance ImagingMaleOsteoarthritis, KneePatellofemoral JointYoung Adultalignmentcartilagegeometrymagnetic resonance imagingosteoarthritispatellofemoral jointpatellofemoral painperfusionstructural abnormalities

Identifiers

PMID32096249
PMCPMC7187437
OpenAlexW3006876723

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.