Evidence map›Paper›PMID 32096099›Full record

ArticleHead and neck pathology2021

Gingival Swelling as the Initial Manifestation of Granulomatosis with Polyangiitis.

Thomas Kertesz, Medha Soowamber, Justin Bubola, David J Psutka, Grace Bradley

Abstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Otolaryngologic manifestations in granulomatosis with Polyangitis: A systematic review of clinical presentations and renal correlation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Oral granulomatosis with polyangiitis a systematic review.Clinical and experimental dental research · 2023
    Pooled it
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas KerteszOral and Maxillofacial Surgery, Trillium Health Partners - Credit Valley Hospital, Mississauga, ON, L5M 2N1, Canada.
Medha SoowamberDepartment of Rheumatology, Internal Medicine, Trillium Health Partners - Credit Valley Hospital, Mississauga, ON, L5M 2N1, Canada.
Justin BubolaOral Pathology and Oral Medicine, Faculty of Dentistry, University of Toronto, 124 Edward St. Room 315C, Toronto, ON, M5G 1G6, Canada.
David J PsutkaOral and Maxillofacial Surgery, Trillium Health Partners - Credit Valley Hospital and Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.
Grace BradleyOral Pathology and Oral Medicine, Faculty of Dentistry, University of Toronto, 124 Edward St. Room 315C, Toronto, ON, M5G 1G6, Canada. grace.bradley@dentistry.utoronto.ca.ORCID http://orcid.org/0000-0002-9008-8696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of granulomatosis with polyangiitis (GPA; formerly named Wegener granulomatosis) that presented initially as florid areas of gingival swelling. The patient also had upper respiratory symptoms that included sinus congestion and cough of recent onset. Clinical-pathologic correlation aided the interpretation of non-specific biopsy findings and immediate referral to an appropriate medical specialist. Treatment was rendered at an early stage of disease with a good response to date. Review of the literature indicates that gingival swelling, often with the characteristic appearance of "strawberry gingivitis" may represent the initial sign of disease in 2% of patients with GPA. Biopsy of gingival lesions often shows a non-specific histologic appearance that should be interpreted in the context of the clinical appearance and pertinent medical history. The clinical investigations that lead to definitive diagnosis and treatment are presented to facilitate the management of this uncommon but potentially fatal condition.

Indexed as

AdultGingivaGranulomatosis with PolyangiitisHumansMaleGingival swellingGranulomatosis with polyangiitisStrawberry gingivitisVasculitisWegener granulomatosis

Identifiers

PMID32096099
PMCPMC8010058

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.