Evidence map›Paper›PMID 32096092›Full record

ArticleNatural products and bioprospecting2020

A New Antimalarial Noreudesmane Sesquiterpenoid from Dobinea delavayi.

Xiu-Rong Wu, Yi Shen, Shu-Jun Cui, Xiao-Lei Luo, Chao-Jiang Xiao, Bei Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Natural products and bioprospecting, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiu-Rong WuInstitute of Materia Medica, Dali University, Xueren Road 2, Dali, 671000, People's Republic of China.
Yi ShenInstitute of Materia Medica, Dali University, Xueren Road 2, Dali, 671000, People's Republic of China.
Shu-Jun CuiInstitute of Materia Medica, Dali University, Xueren Road 2, Dali, 671000, People's Republic of China.
Xiao-Lei LuoInstitute of Materia Medica, Dali University, Xueren Road 2, Dali, 671000, People's Republic of China.
Chao-Jiang XiaoCollege of Pharmacy and Chemistry, Dali University, Xueren Road 2, Dali, 671000, People's Republic of China. xiaochaojiang@yeah.net.ORCID http://orcid.org/0000-0001-5540-2339
Bei JiangInstitute of Materia Medica, Dali University, Xueren Road 2, Dali, 671000, People's Republic of China. jiangbei@dali.edu.cn.ORCID http://orcid.org/0000-0002-4036-0735

Funding

National Natural Science Foundation of China 81460532National Natural Science Foundation of China 81960637the Innovation Team Project of Dali University for the Development and Utilization of Characteristic Medicinal Plants in Western Yunnan & Bai Nationality Medicines ZKLX2019106
6 · The paper itself

Abstract

One previously undescribed angeloylated noreudesmane sesquiterpenoid, dobinin O (1), along with four known eudesmane sesquiterpenoids (2-5) were isolated from the peeled roots of Dobinea delavayi. Their structures were elucidated by extensive spectroscopic data analyses. In addition, compound 1 exhibited moderate antimalarial activity against Plasmodium yoelii BY265RFP with the inhibition ratio of 17.8 ± 13.3% at the dose of 30 mg/kg/day.

Indexed as

AnacardiaceaeAntimalarial activityDobinea delavayiNoreudesmane sesquiterpenoid

Identifiers

PMID32096092
PMCPMC7176782

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.