ArticleCerebellum (London, England)2020
Pallidal Activity in Cervical Dystonia with and Without Head Tremor.
Article in Cerebellum (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Tremor: Clinical Frameworks, Network Dysfunction and Therapeutics.Brain sciences · 2025Review
- Brain network pathophysiology in dystonia.Dystonia (Lausanne, Switzerland) · 2025Article
- Article
- Dystonic Tremor: Time to Change.Movement disorders clinical practice · 2024Review
- Effects of neck proprioceptive modulation on pallidal network connectivity in dystonia.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2023Article
- Pallidal Recordings in Chronically Implanted Dystonic Patients: Mitigation of Tremor-Related Artifacts.Bioengineering (Basel, Switzerland) · 2023Article
- Article
- Milestones in Tremor Research: 10 Years Later.Movement disorders clinical practice · 2022Review
- Clinical features, pathophysiology, treatment, and controversies of tremor in dystonia.Journal of the neurological sciences · 2022Review
- Head tremor in cervical dystonia: Quantifying severity with computer vision.Journal of the neurological sciences · 2022Article
- Multimodal imaging of essential tremor and dystonic tremor.NeuroImage. Clinical · 2022Article
- Cerebello-thalamic activity drives an abnormal motor network into dystonic tremor.NeuroImage. Clinical · 2022Article
- Pallidal neuron activity determines responsiveness to deep brain stimulation in cervical dystonia.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Improvement of head and neck range of motion induced by chronic pallidal deep brain stimulation for cervical dystonia.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- Non-invasive suppression of essential tremor via phase-locked disruption of its temporal coherence.Nature communications · 2021Article
- Cortical Oscillations in Cervical Dystonia and Dystonic Tremor.Cerebral cortex communications · 2020Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
Abstract
The relationship between two common movement disorders, dystonia and tremor, is controversial. Both deficits have correlates in the network that includes connections between the cerebellum and the basal ganglia. In order to assess the physiological relationship between tremor and dystonia, we measured the activity of 727 pallidal single-neurons during deep brain stimulation surgery in patients with cervical dystonia without head oscillations, cervical dystonia plus jerky oscillations, and cervical dystonia with sinusoidal oscillations. Cluster analyses of spike-train recordings allowed classification of the pallidal activity into burst, pause, and tonic. Burst neurons were more common, and number of spikes within spike and inter-burst intervals was shorter in pure dystonia and jerky oscillation groups compared to the sinusoidal oscillation group. Pause neurons were more common and irregular in pure tremor group compared to pure dystonia and jerky oscillation groups. There was bihemispheric asymmetry in spontaneous firing discharge in pure dystonia and jerky oscillation groups, but not in sinusoidal oscillation group. These results demonstrate that the physiology of pallidal neurons in patients with pure cervical dystonia is similar to those who have cervical dystonia combined with jerky oscillations, but different from those who have cervical dystonia combined with sinusoidal oscillations. These results imply distinct mechanistic underpinnings for different types of head oscillations in cervical dystonia.
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Registered trials
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