Evidence map›Paper›PMID 32095935›Full record

Trial reportEuropean journal of applied physiology2020

Effects of green tea extract supplementation and endurance training on irisin, pro-inflammatory cytokines, and adiponectin concentrations in overweight middle-aged men.

Reza Bagheri, Amir Rashidlamir, Damoon Ashtary-Larky, Alexei Wong, Brandon Grubbs, Mohamad S Motevalli, Julien S Baker, Ismail Laher, Hassane Zouhal

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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  8. Effects of Ramadan Intermittent Fasting on Gut Hormones and Body Composition in Males with Obesity.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

Reza BagheriDepartment of Exercise Physiology, University of Isfahan, Isfahan, Iran.
Amir RashidlamirDepartment of Exercise Physiology, Ferdowsi University of Mashhad, Mashhad, Iran. Rashidlamir@um.ac.ir.
Damoon Ashtary-LarkyNutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Alexei WongDepartment of Health and Human Performance, Marymount University, Arlington, VA, USA.
Brandon GrubbsDepartment of Health and Human Performance, Middle Tennessee State University, Murfreesboro, TN, USA.
Mohamad S MotevalliDepartment of Exercise Physiology, Ferdowsi University of Mashhad, Mashhad, Iran.
Julien S BakerCentre for Health and Exercise Science Research, Department of Sport, Physical Education and Health, Hong Kong Baptist University, Kowloon Tong,, Hong Kong.
Ismail LaherDepartment of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Hassane ZouhalUniv Rennes, M2S (Laboratoire Mouvement, Sport, Santé) - EA 1274, 35000, Rennes, France. hassane.zouhal@univ-rennes2.fr.ORCID http://orcid.org/0000-0001-6743-6464
Ferdowsi University of Mashhad · IRAhvaz Jundishapur University of Medical Sciences · IRHong Kong Baptist University · HKMarymount University · USMiddle Tennessee State University · USUniversité Rennes 2 · FRUniversity of British Columbia · CAUniversity of Isfahan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGreen tea extract (GTE) supplementation has been proposed to possess anti-inflammatory properties. This study assessed the effects of GTE on endurance training (ET) induced changes on irisin, pro-inflammatory cytokines, adiponectin and anthropometric indices in overweight middle-aged males.

methodsParticipants were randomly assigned to three groups (n = 15): endurance training + placebo (ET + P), endurance training + green tea extract supplementation (ET + GTE), and no endurance training + placebo (P). The ET intervention consisted of an 8-week training program that included circuit training, fast walking or jogging performed three times/week at a moderate intensity (40-59% of the heart rate reserve). Participants received 500 mg/day GTE using a green tea capsule. Serum concentrations of interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-α), irisin, adiponectin, and high-sensitivity C-reactive protein (hs-CRP) were measured prior to and after the 8-week training intervention.

resultsBoth exercise interventions decreased IL-6 and hs-CRP (p < 0.05), and increased adiponectin (p < 0.01) levels; changes in these variables were greater in the ET + GTE group compared to the ET + P and P groups (p < 0.01). Irisin concentrations increased only in the ET + GTE group and were different from the ET + P and P groups (p < 0.01). There were no changes in TNF-α concentrations in any of the groups. Both exercise interventions (ET + GTE and ET + P) decreased bodyweight, body mass index (BMI), body fat percentage (BFP), and visceral fat area (VFA) (p < 0.05), with greater changes in these variables occurring in the ET + GTE group compared to ET + P and P groups (p < 0.01).

conclusionThe combination of GTE supplementation and ET produces beneficial anti-inflammatory and metabolic effects, which were greater than those produced by ET alone.

Indexed as

Camellia sinensisEndurance TrainingAdipokinesAdultBiomarkersBody CompositionC-Reactive ProteinFibronectinsHumansInflammationMaleMiddle AgedOverweightPhytotherapyPlant ExtractsAdipokinesBiomarkersC-Reactive ProteinFibronectinsFNDC5 protein, humanPlant ExtractsExerciseGreen tea extractInflammationObesity

Identifiers

PMID32095935
OpenAlexW3008040459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.