Evidence map›Paper›PMID 32095867›Full record

ArticleEuropean journal of nutrition2020

Magnesium intake is inversely associated with risk of obesity in a 30-year prospective follow-up study among American young adults.

Liping Lu, Cheng Chen, Kefeng Yang, Jie Zhu, Pengcheng Xun, James M Shikany, Ka He

Open access · greenAbstract read
In one paragraph

Article in European journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Magnesium: Hype and Health Benefits.Current nutrition reports · 2026
    Review
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  18. Serum Magnesium is Inversely Associated with Body Composition and Metabolic Syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Liping LuDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, USA.
Cheng ChenDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, USA.
Kefeng YangDepartment of Clinical Nutrition, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jie ZhuNutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX, USA.
Pengcheng XunDepartment of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
James M ShikanyDivision of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Ka HeDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, USA. kk3399@cumc.columbia.edu.ORCID http://orcid.org/0000-0003-1451-3889
Columbia University Irving Medical Center · USIndiana University Bloomington · USShanghai Jiao Tong University · CNTexas State University · USUniversity of Alabama at Birmingham · US

Funding

Trace mineral levels, the trajectory of cognitive decline and telomere attritionRF1AG056111 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI KAHE, KA · 2017 to 2017
$3.1M
Trace mineral levels, metabolomics, and diabetes riskR01DK116603 · NIDDK · TRUSTEES OF INDIANA UNIVERSITY · PI KAHE, KA · 2018 to 2019
$1.5M
NHLBI NIH HHS HHSN26820100004INHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INIA NIH HHS RF1 AG056111NIDDK NIH HHS R01 DK116603NIH HHS R01AG056111NIH HHS R01DK116603
6 · The paper itself

Abstract

purposeAlthough laboratory studies suggest a potential role of magnesium (Mg) in weight regulation, human studies relating Mg intake to body weight are limited. This study sought to prospectively examine the association between Mg intake and incidence of obesity and related anthropometric and biochemical indicators.

methodsThe Coronary Artery Risk Development in Young Adults (CARDIA) study recruited 5115 American young adults, aged 18-30 years, at baseline in 1985-6, and re-examined them in eight follow-ups. Incident obesity was defined as body mass index (BMI) ≥ 30 kg/m

resultsDuring the 30-year follow-up, 1675 incident cases of obesity were identified. After adjustment for potential confounders, Mg intake was inversely associated with incidence of obesity. The multivariable-adjusted hazard ratios (95% confidence interval) from quintile 1 (Q1) (lowest intake group) to quintile 5 (Q5) (highest intake group) were 1 (referent), 0.86 (0.74, 1.00), 0.83 (0.71, 0.97), 0.55 (0.46, 0.66), and 0.49 (0.40, 0.60); P for trend < 0.01. Consistently, Mg intake was inversely associated with the levels of BMI, triceps skinfold, suprailiac skinfold, subscapular skinfold, fasting insulin, and C-reactive protein. The observed associations were not materially modified by age, sex, race, or BMI at baseline. In addition, the intakes of foods rich in Mg, including whole grains, nuts and seeds, legumes, and dark-green vegetables, were associated with lower incidence of obesity.

conclusionsThis longitudinal study suggests that Mg intake is inversely associated with incidence of obesity.

Indexed as

MagnesiumObesityBody Mass IndexDietFollow-Up StudiesHumansLongitudinal StudiesProspective StudiesRisk FactorsUnited StatesYoung AdultMagnesiumBody mass indexDietMagnesiumObesityYoung adults

Identifiers

PMID32095867
PMCPMC7483156
OpenAlexW3007990983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.