Evidence map›Paper›PMID 32095630›Full record

ArticleFood and waterborne parasitology2019

Elevated incidence of alveolar echinococcosis in immunocompromised patients.

A Lachenmayer, D Gebbers, B Gottstein, D Candinas, G Beldi

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Food and waterborne parasitology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Observational
  3. Epidemiological and clinical characteristics of patients in the alveolar echinococcosis registry, France, 1982 to 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. A Rare Cause of Alveolar Echinococcal Metastasis.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Combined cross-sectional and case-control study onVeterinary parasitology: X · 2020
    Article
  15. Article
  16. Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis.International journal for parasitology. Drugs and drug resistance · 2020
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

A LachenmayerDepartment of Visceral Surgery and Medicine, University Hospital Bern, University of Bern, Bern, Switzerland.
D GebbersDepartment of Visceral Surgery and Medicine, University Hospital Bern, University of Bern, Bern, Switzerland.
B GottsteinInstitute of Parasitology, Vetsuisse Faculty, University of Bern, Länggass-Strasse 122, 3012, Bern, Switzerland.
D CandinasDepartment of Visceral Surgery and Medicine, University Hospital Bern, University of Bern, Bern, Switzerland.
G BeldiDepartment of Visceral Surgery and Medicine, University Hospital Bern, University of Bern, Bern, Switzerland.
University of Bern · CHUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecent experimental data has revealed that the course of alveolar echinococcosis (AE) depends on adaptive immunity. For this study, we aimed to analyze the incidence and outcome of AE in immunocompromised humans. MATERIAL AND

methodsRetrospective analysis of 131 patients with a median age of 54 years treated for AE between 1971 and 2017 at a Swiss tertiary referral Centre. Fifty-two percent were females and 65 patients (50%) were diagnosed incidentally. Fourteen patients (16%) were operated on laparoscopically. Overall, median follow-up was 48 months.

resultsNew diagnoses have increased fourfold in immunocompetent and tenfold in immunocompromised patients in the past decade (

conclusionThe incidence of human AE has increased over the last 2 decades with surgical interventions resulting in excellent outcomes. We have observed an association of immunosuppressive conditions with both incidence and survival of AE eventually justifying the implementation of a screening program for patients at risk in endemic regions.

Indexed as

alveolar_echinococcosisAlveolar echinococcosis, (AE)Benzimidazolebenzimidazole, (BZM)EchinoccocosisEchinococcus multilocularisEchinococcus multilocularis, (E. multilocularis)immunocompetent, (ICT)immunocompromised, (ICR)Immunosuppression

Identifiers

PMID32095630
PMCPMC7034048
OpenAlexW2947162647

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.