Evidence map›Paper›PMID 32095569›Full record

ArticleTechnical innovations & patient support in radiation oncology2018

Reduction of intra-fraction prostate motion - Determining optimal bladder volume and filling for prostate radiotherapy using daily 4D TPUS and CBCT.

Eric Pei Ping Pang, Kellie Knight, Ashik Hussain, Qiao Fan, Marilyn Baird, Sheena Xue Fei Tan, Wing-Ho Mui, Ronnie Wing-Kin Leung, Irene Kai Ling Seah, Zubin Master and 1 more

Abstract read
In one paragraph

Article in Technical innovations & patient support in radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Duration-dependent margins for prostate radiotherapy-a practical motion mitigation strategy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Trial
  2. Deep learning-based prediction of interfractional anatomic variations in prostate cancer radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
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  12. Impact of prostate focused alignment on planned pelvic lymph node dose.Journal of applied clinical medical physics · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eric Pei Ping PangFaculty of Medicine, Nursing and Health Sciences, Department of Medical Imaging & Radiation Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia.
Kellie KnightFaculty of Medicine, Nursing and Health Sciences, Department of Medical Imaging & Radiation Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia.
Ashik HussainDivision of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore.
Qiao FanCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, 8 College Road, Singapore 169857, Singapore.
Marilyn BairdFaculty of Medicine, Nursing and Health Sciences, Department of Medical Imaging & Radiation Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia.
Sheena Xue Fei TanDivision of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore.
Wing-Ho MuiTuen Mun Hospital, Hong Kong, 23 Tsing Chung Koon Road, Tuen Mun, New Territories, Hong Kong.
Ronnie Wing-Kin LeungTuen Mun Hospital, Hong Kong, 23 Tsing Chung Koon Road, Tuen Mun, New Territories, Hong Kong.
Irene Kai Ling SeahDivision of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore.
Zubin MasterDivision of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore.
Jeffrey Kit Loong TuanDivision of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeInconsistent bladder and rectal volumes have been associated with motion uncertainties during prostate radiotherapy. This study investigates the impact of these volumes to determine the optimal bladder volume. MATERIALS AND

methods60 patients from two Asian hospitals were recruited prospectively. 1887 daily cone-beam computed tomography (CBCT) images were analysed. Intra-fraction motion of the prostate was monitored real-time using a four-dimension transperineal ultrasound (4D TPUS) Clarity® system. The impact of planned bladder volume, adequacy of daily bladder filling, and rectum volume on mean intra-fraction motion of the prostate was analysed. Patients' ability to comply with the full bladder hydration protocol and level of frustration was assessed using a questionaire. Acute side effects were assessed using the Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 and quality of life (QoL) assessed using the International Prostate Symptom Score (IPSS).

resultsThe mean (SD) bladder and rectum volumes achieved during daily treatment were 139.7 cm

conclusionsA planned bladder volume >200 cm

Indexed as

4D TPUS clarityFull bladder hydration protocolIntra-fraction motionProstate radiotherapyReal-time tracking

Identifiers

PMID32095569
PMCPMC7033810

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.