ArticleTechnical innovations & patient support in radiation oncology
A dose based approach for evaluation of inter-observer variations in target delineation.
Article in Technical innovations & patient support in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Deep learning segmentation of the cerebral ventricular system and brainstem for pediatric radiotherapy planning.Physics and imaging in radiation oncology · 2026Article
- Resection cavity auto-contouring for patients with pediatric medulloblastoma using only CT information.Journal of applied clinical medical physics · 2023Article
- Combining inter-observer variability, range and setup uncertainty in a variance-based sensitivity analysis for proton therapy.Physics and imaging in radiation oncology · 2021Article
- Challenges in the target volume definition of lung cancer radiotherapy.Translational lung cancer research · 2021Review
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Authors and funding
9 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeSubstantial inter-observer variations in target delineation have been presented previously. Target delineation for paediatric cases is difficult due to the small number of children, the variation in paediatric targets, the number of study protocols, and the individual patient's specific needs and demands. Uncertainties in target delineation might lead to under-dosage or over-dosage. The aim of this work is to apply the concept of a consensus volume and good quality treatment plans to visualise and quantify inter-observer target delineation variations in dosimetric terms in addition to conventional geometrically based volume concordance indices. MATERIAL AND
methodsTwo paediatric cases were used to demonstrate the potential of adding dose metrics when evaluating target delineation diversity; Hodgkin's disease (case 1) and rhabdomyosarcoma of the parotid gland (case 2). The variability in target delineation (PTV delineations) between six centres was quantified using the generalised conformity index,
resultsA considerable variation in target segmentation was seen in both cases. For case 1 the variation was 374-960 cm
conclusionsThe DVHs in absolute volume add valuable and easily understood information to various indices for evaluating uniformity in target delineation.
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Registered trials
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