ArticleTransplantation direct2019
Whole Body CT Imaging in Deceased Donor Screening for Malignancies.
Article in Transplantation direct, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- The Value of Chest and Abdominal CT Scans in Deceased Organ Donor Screening: A Prospective Nationwide Cohort Study.Transplantation direct · 2025Article
- Analysis of Unused Organ Donors in the Netherlands: Older Donor Age Associated With Higher Risk of Non-Utilization.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Treatment of Complex Desmoid Tumors in Familial Adenomatous Polyposis Syndrome by Intestinal Transplantation.Transplantation direct · 2024Article
- Changes in the Percentage of Patients Treated for Cancer Before and After the SARS-CoV-2 Epidemic: A Retrospective Observational Study.Juntendo Iji zasshi = Juntendo medical journal · 2024Article
- Radiological Screening Methods in Deceased Organ Donation: An Overview of Guidelines Worldwide.Transplant international : official journal of the European Society for Organ Transplantation · 2022Review
- Reply to: Balancing Cost and Efficiency in Screening Potential Organ Donors With Whole Body CT.Transplantation direct · 2020Article
- Balancing Cost and Efficiency in Screening Potential Organ Donors With Whole Body CT.Transplantation direct · 2020Article
- Erratum: Whole Body CT Imaging in Deceased Donor Screening for Malignancies: Erratum.Transplantation direct · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn most western countries, the median donor age is increasing. The incidence of malignancies in older populations is increasing as well. To prevent donor-derived malignancies we evaluated radiologic donor screening in a retrospective donor cohort.
methodsThis study analyzes the efficacy of a preoperative computed tomography (CT) scan on detecting malignancies. All deceased organ donors in the Netherlands between January 2013 and December 2017 were included. Donor reports were analyzed to identify malignancies detected before or during organ procurement. Findings between donor screening with or without CT-scan were compared.
resultsChest or abdominal CT-scans were performed in 17% and 18% of the 1644 reported donors respectively. Screening by chest CT-scan versus radiograph resulted in 1.5% and 0.0% detected thoracic malignancies respectively. During procurement no thoracic malignancies were found in patients screened by chest CT compared with 0.2% malignancies in the radiograph group. Screening by abdominal CT-scan resulted in 0.0% malignancies, compared with 0.2% in the abdominal ultrasound group. During procurement 1.0% and 1.3% malignancies were found in the abdominal CT-scan and ultrasound groups, respectively.
conclusionsScreening by CT-scan decreased the perioperative detection of tumors by 30%. A preoperative CT-scan may be helpful by providing additional information on (aberrant) anatomy to the procuring or transplanting surgeon. In conclusion, donor screening by CT-scan could decrease the risk of donor-derived malignancies and prevents unnecessary procurements per year in the Netherlands.
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Registered trials
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