ArticleJournal of oral biology and craniofacial research
Age and gender characteristics of the biochemical composition of saliva: Correlations with the composition of blood plasma.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Salivary flow rate in children and teenagers with Down syndrome: Systematic review and meta-analysis.Brazilian oral research · 2025Pooled it
- The role of salivary lactoferrin as a potential biomarker for periodontal disease: a systematic review and meta-analysis.Frontiers in oral health · 2026Review
- Sensitive Colorimetric Lateral Flow Assays Enabled by Platinum-Group Metal Nanoparticles with Peroxidase-Like Activities.Advanced healthcare materials · 2025Article
- Influence of gender and combined estrogen-progestin oral contraceptive on parotid saliva flow rate, pH, and electrolytes concentration.Clinical and experimental dental research · 2024Article
- Oxidative imbalance as a co-player in jaw functional limitations and biopsychosocial profile in patients with temporomandibular disorder-myofascial pain with referral.Frontiers in neurology · 2024Article
- Human Serum and Salivary Metabolomes: Diversity and Closeness.International journal of molecular sciences · 2023Article
- Biomarkers in Body Fluids as Indicators of Skeletal Maturity: A Systematic Review and Meta-analysis.Rambam Maimonides medical journal · 2023Review
- Biomolecular sensors for advanced physiological monitoring.Nature reviews bioengineering · 2023Review
- Hijama (wet cupping therapy) enhances oral and dental health by improving salivary secretion volume and pH in adult patients at King Abdul Aziz University Hospital (KAUH), Jeddah, KSA: A controlled trial study.Journal of Taibah University Medical Sciences · 2023Article
- Salivary Concentrations of Chemerin, α-Defensin 1, and TNF-α as Potential Biomarkers in the Early Diagnosis of Colorectal Cancer.Metabolites · 2022Article
- An integrated analysis and comparison of serum, saliva and sebum for COVID-19 metabolomics.Scientific reports · 2022Article
- «Salivaomics» of Different Molecular Biological Subtypes of Breast Cancer.Current issues in molecular biology · 2022Article
- Prognostic Value of Salivary Biochemical Indicators in Primary Resectable Breast Cancer.Metabolites · 2022Article
- Impact of body fat, body water content, and skeletal muscle mass index on peak salivary lactate levels after squat jump exercise in healthy non-athlete adult males.BMC sports science, medicine & rehabilitation · 2022Article
- Attenuated total reflection FTIR dataset for identification of type 2 diabetes using saliva.Computational and structural biotechnology journal · 2022Article
- Saliva pH and Flow Rate in Patients with Periodontal Disease and Associated Cardiovascular Disease.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Analysis of Saliva Lipids in Breast and Prostate Cancer by IR Spectroscopy.Diagnostics (Basel, Switzerland) · 2021Article
- A review of potential biomarkers for assessing physical and psychological trauma in paediatric burns.Burns & trauma · 2021Review
- Salivary exosomes: properties, medical applications, and isolation methods.Molecular biology reports · 2020Review
- Age- and Periodontal Disease Independent Correlation of Salivary Amino Acids.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, the attention of researchers to the study of the properties of human saliva, as a material with unique properties and diagnostic capabilities, has increased. RESEARCH
objectiveto study the connection of the biochemical composition of saliva and blood plasma in the norm, depending on gender and age.
methods107 volunteers took part in the study, including 46 female (37.2 ± 3.9 years old) and 61 male (36.1 ± 2.8 years old). In all samples of saliva and blood plasma, 16 biochemical parameters were determined, including mineral and protein composition, enzyme activity. Non-parametric statistical methods were used to process the data.
resultsIt has been shown that it is difficult to establish an unambiguous relation between biochemical parameters of saliva and blood plasma. The calculation of the Spearman correlation coefficients showed that only 7 of the 16 parameters demonstrate the presence of a weak correlation between the content in saliva and plasma.
conclusionIn general, the determination of the composition of saliva may have an independent diagnostic value; in this case, drawing a parallel with the composition of serum and blood plasma is not advisable. Nevertheless, the use of saliva in clinical laboratory diagnostics is associated with the need to establish criteria for the norm and pathology for each biochemical parameter.
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