Evidence map›Paper›PMID 32095286›Full record

ArticleInternational journal of nephrology2020

Serum Sclerostin, Body Composition, and Sarcopenia in Hemodialysis Patients with Diabetes.

Maria Carolina Medeiros, Natalia Rocha, Elba Bandeira, Isabel Dantas, Conceição Chaves, Mario Oliveira, Francisco Bandeira

Open access · goldAbstract read
In one paragraph

Article in International journal of nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Bone as an endocrine regulator of lipid and energy metabolism.Reviews in endocrine & metabolic disorders · 2026
    Review
  5. Article
  6. Rethinking Osteoporosis Drugs: Can We Simultaneously Address Sarcopenia?International journal of molecular sciences · 2025
    Review
  7. Bone and muscle crosstalk in ageing and disease.Nature reviews. Endocrinology · 2025
    Review
  8. Review
  9. Sclerostin: clinical insights in muscle-bone crosstalk.The Journal of international medical research · 2023
    Review
  10. Role of the Osteocyte in Musculoskeletal Disease.Current osteoporosis reports · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Review
  17. Review
  18. Role of myokines and osteokines in cancer cachexia.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  19. Article
  20. Bone-Muscle Mutual Interactions.Current osteoporosis reports · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maria Carolina MedeirosDivision of Endocrinology and Diabetes, Agamenon Magalhaes Hospital, University of Pernambuco Medical School, Recife, Brazil.
Natalia RochaDivision of Endocrinology and Diabetes, Agamenon Magalhaes Hospital, University of Pernambuco Medical School, Recife, Brazil.
Elba BandeiraDivision of Endocrinology and Diabetes, Agamenon Magalhaes Hospital, University of Pernambuco Medical School, Recife, Brazil.
Isabel DantasDivision of Endocrinology and Diabetes, Agamenon Magalhaes Hospital, University of Pernambuco Medical School, Recife, Brazil.ORCID https://orcid.org/0000-0001-8286-4897
Conceição ChavesDepartment of Nutrition, Federal University of Pernambuco, Recife, Brazil.
Mario OliveiraUninefron-Unidade Nefrológica, Recife, Brazil.
Francisco BandeiraDivision of Endocrinology and Diabetes, Agamenon Magalhaes Hospital, University of Pernambuco Medical School, Recife, Brazil.ORCID https://orcid.org/0000-0003-0290-0742
Universidade de Pernambuco · BRUniversidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sclerostin (Scl) is an osteoblast-inhibiting glycoprotein that is secreted mainly by osteocytes and is regulated by hormonal changes and skeletal loading. Decreased physical function and high serum Scl concentrations have been reported in chronic renal failure patients but little is known to date about the differences between diabetic and non-diabetic patients on hemodialysis who are susceptible to both sarcopenia and bone fragility.

Identifiers

PMID32095286
PMCPMC7035555
OpenAlexW3005144470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.