Evidence map›Paper›PMID 32095260›Full record

ArticleJFMS open reports

Suspected hepatopathy and pancreatitis associated with mycophenolate mofetil use in a cat with immune-mediated haemolytic anaemia.

Matthew A Kopke, Pru E J Galloway

Open access · goldAbstract readCase Reports
In one paragraph

Article in JFMS open reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew A KopkeSchool of Veterinary Science, Massey University, Palmerston North, New Zealand.ORCID https://orcid.org/0000-0002-1712-9615
Pru E J GallowayCATMED, Lower Hutt, New Zealand.
Massey University · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

case summaryA 5-year-old spayed female domestic shorthair cat was referred for severe anaemia. Findings on initial work-up were consistent with a diagnosis of idiopathic immune-mediated haemolytic anaemia. A combination of prednisolone and mycophenolate mofetil (MMF) was instituted. On revisit approximately 2 months later, red blood cell parameters were normal, but the plasma was described as icteric, prompting further investigation. Concurrent hepatopathy and pancreatitis were diagnosed, suspected as being adverse reactions to MMF, as has been reported with use of the drug in humans. Resolution of serum biochemistry abnormalities took approximately 2 months, following discontinuing MMF. At the time of writing, the cat remained clinically well 1 year after initial presentation. RELEVANCE AND NOVEL INFORMATION: With increasing use of MMF as an immunosuppressive agent in cats, clinicians should be aware of both common and potentially rare adverse effects, such as those described herein. In addition, suitable monitoring tools need to be in place to facilitate early detection and appropriate management.

Indexed as

Adverse reactionhepatotoxicityIMHAimmune-mediated haemolytic anaemiaimmunosuppressive therapymonitoringmycophenolic acidside effect

Identifiers

PMID32095260
PMCPMC7013118
OpenAlexW3006276980

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.