Evidence map›Paper›PMID 32094586›Full record

ArticleNature microbiology2020

FttA is a CPSF73 homologue that terminates transcription in Archaea.

Travis J Sanders, Breanna R Wenck, Jocelyn N Selan, Mathew P Barker, Stavros A Trimmer, Julie E Walker, Thomas J Santangelo

Open access · greenAbstract read
In one paragraph

Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Toward structural understanding of eukaryotic transcription elongation.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Travis J SandersDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Breanna R WenckDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Jocelyn N SelanDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Mathew P BarkerDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Stavros A TrimmerDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Julie E WalkerDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Thomas J SantangeloDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA. thomas.santangelo@colostate.edu.ORCID http://orcid.org/0000-0003-4559-3244
Colorado State University · USWorld Water Watch · US

Funding

Mechanisms of Archaeal Transcription Termination - Administrative SupplementR01GM100329 · NIGMS · OHIO STATE UNIVERSITY · PI SANTANGELO, THOMAS JAMES · 2012 to 2021
$2.5M
Regulation of Archaeal TranscriptionR35GM143963 · NIGMS · COLORADO STATE UNIVERSITY · PI Thomas James Santangelo · 2022 to 2026
$1.8M
NIGMS NIH HHS R01 GM100329NIGMS NIH HHS R35 GM143963
6 · The paper itself

Abstract

Regulated gene expression is largely achieved by controlling the activities of essential, multisubunit RNA polymerase transcription elongation complexes (TECs). The extreme stability required of TECs to processively transcribe large genomic regions necessitates robust mechanisms to terminate transcription. Efficient transcription termination is particularly critical for gene-dense bacterial and archaeal genomes

Indexed as

Genome, ArchaealTranscription Termination, GeneticArchaeal ProteinsBacteriaBiological EvolutionCleavage And Polyadenylation Specificity FactorDNA-Directed RNA PolymerasesHumansModels, MolecularProtein BiosynthesisRNA, MessengerStructural Homology, ProteinThermococcusTranscription Elongation, GeneticTranscription FactorsTranscription Initiation, GeneticArchaeal ProteinsCleavage And Polyadenylation Specificity FactorCPSF3 protein, humanDNA-Directed RNA PolymerasesRNA, MessengerTranscription Factors

Identifiers

PMID32094586
PMCPMC7103508
OpenAlexW3007534620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.