Evidence map›Paper›PMID 32094539›Full record

ArticleNature ecology & evolution2020

The spread of steppe and Iranian-related ancestry in the islands of the western Mediterranean.

Daniel M Fernandes, Alissa Mittnik, Iñigo Olalde, Iosif Lazaridis, Olivia Cheronet, Nadin Rohland, Swapan Mallick, Rebecca Bernardos, Nasreen Broomandkhoshbacht, Jens Carlsson and 42 more

Erratum issuedAbstract read
In one paragraph

Article in Nature ecology & evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Estimating human mobility in Holocene Western Eurasia with large-scale ancient genomic data.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Pooled it
  2. Article
  3. Article
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  5. The persistence and loss of hard selective sweeps amid admixture in ancient Eurasians.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. On the Edge of Empire: Paleogenomic Insights into Roman Dacia.bioRxiv : the preprint server for biology · 2026
    Article
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  9. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

52 authors.

Daniel M FernandesDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria. daniel.fernandes@univie.ac.at.ORCID http://orcid.org/0000-0002-7434-6552
Alissa MittnikDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6963-4824
Iñigo OlaldeDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Iosif LazaridisDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Olivia CheronetDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Nadin RohlandDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Swapan MallickDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Rebecca BernardosDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-4625-3727
Nasreen BroomandkhoshbachtDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-5350-1608
Jens CarlssonArea 52 Research Group, School of Biology and Environmental Science/Earth Institute, University College Dublin, Dublin, Ireland.
Brendan J CulletonInstitutes of Energy and the Environment, The Pennsylvania State University, University Park, PA, USA.
Matthew FerryDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Beatriz GamarraEarth Institute and School of Archaeology, University College Dublin, Dublin, Ireland.
Martina LariDipartimento di Biologia, Università di Firenze, Florence, Italy.
Matthew MahDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8987-6436
Megan MichelDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Alessandra ModiDipartimento di Biologia, Università di Firenze, Florence, Italy.ORCID http://orcid.org/0000-0001-9514-9868
Mario NovakEarth Institute and School of Archaeology, University College Dublin, Dublin, Ireland.
Jonas OppenheimerDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Kendra A SirakEarth Institute and School of Archaeology, University College Dublin, Dublin, Ireland.
Kristin StewardsonDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Kirsten MandlDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Constanze SchattkeDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Kadir T ÖzdoğanDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Michaela LucciDANTE Laboratory of Diet and Ancient Technology, Sapienza University of Rome, Rome, Italy.
Gabriella GasperettiSuperintendency of Archaeology, Fine Arts and Landscape for the provinces of Sassari and Nuoro, Sassari, Italy.
Francesca CandilioSuperintendency of Archaeology, Fine Arts and Landscape for the city of Cagliari and the provinces of Oristano and South Sardinia, Cagliari, Italy.ORCID http://orcid.org/0000-0002-4668-1361
Gianfranca SalisSuperintendency of Archaeology, Fine Arts and Landscape for the city of Cagliari and the provinces of Oristano and South Sardinia, Cagliari, Italy.
Stefania VaiDipartimento di Biologia, Università di Firenze, Florence, Italy.ORCID http://orcid.org/0000-0003-3844-5147
Edgard CamarósInstituto Internacional de Investigaciones Prehistóricas de Cantabria, Universidad de Cantabria-Gobierno de Cantabria-Banco Santander, Santander, Spain.ORCID http://orcid.org/0000-0002-0119-3807
Carla CalòDipartimento di Scienze della Vita e dell' Ambiente, Sezione di Neuroscienze e Antropologia, Universita' di Cagliari, Cagliari, Italy.
Giulio CatalanoDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, Palermo, Italy.
Marián CuetoInstituto Internacional de Investigaciones Prehistóricas de Cantabria, Universidad de Cantabria-Gobierno de Cantabria-Banco Santander, Santander, Spain.ORCID http://orcid.org/0000-0001-7989-9925
Vincenza ForgiaDipartimento Culture e Società, Università di Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0003-1121-2706
Marina LozanoInstitut Català de Paleoecologia Humana i Evolució Social (IPHES), Tarragona, Spain.ORCID http://orcid.org/0000-0002-6304-7848
Elisabetta MariniDipartimento di Scienze della Vita e dell' Ambiente, Sezione di Neuroscienze e Antropologia, Universita' di Cagliari, Cagliari, Italy.
Margherita MichelettiDipartimento di Scienze della Vita e Biologia dei Sistemi, Università di Torino, Torino, Italy.
Roberto M MiccichèDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0002-2485-2019
Maria R PalomboCNR-Istituto di Geologia Ambientale e Geoingegneria c/o Dipartimento di Scienze della Terra, Sapienza Università di Roma, Rome, Italy.
Damià RamisIndependent researcher, Palma de Mallorca, Spain.
Vittoria SchimmentiMuseo Archeologico Regionale Antonino Salinas, Palermo, Italy.
Pau SuredaInstituto de Ciencias del Patrimonio (Incipit-CSIC), Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0003-4366-6489
Luís TeiraInstituto Internacional de Investigaciones Prehistóricas de Cantabria, Universidad de Cantabria-Gobierno de Cantabria-Banco Santander, Santander, Spain.
Maria Teschler-NicolaDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Douglas J KennettDepartment of Anthropology, University of California, Santa Barbara, Santa Barbara, CA, USA.
Carles Lalueza-FoxInstitute of Evolutionary Biology, CSIC-Universitat Pompeu Fabra, Barcelona, Spain.ORCID http://orcid.org/0000-0002-1730-5914
Nick PattersonBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Luca SineoDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0001-8634-2295
Alfredo CoppaDepartment of Environmental Biology, Sapienza University of Rome, Rome, Italy.
David CaramelliDipartimento di Biologia, Università di Firenze, Florence, Italy. david.caramelli@unifi.it.ORCID http://orcid.org/0000-0001-6468-1675
Ron PinhasiDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria. ron.pinhasi@univie.ac.at.ORCID http://orcid.org/0000-0003-1629-8131
David ReichDepartment of Genetics, Harvard Medical School, Boston, MA, USA. reich@genetics.med.harvard.edu.ORCID http://orcid.org/0000-0002-7037-5292

Funding

Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

Steppe-pastoralist-related ancestry reached Central Europe by at least 2500 BC, whereas Iranian farmer-related ancestry was present in Aegean Europe by at least 1900 BC. However, the spread of these ancestries into the western Mediterranean, where they have contributed to many populations that live today, remains poorly understood. Here, we generated genome-wide ancient-DNA data from the Balearic Islands, Sicily and Sardinia, increasing the number of individuals with reported data from 5 to 66. The oldest individual from the Balearic Islands (~2400 BC) carried ancestry from steppe pastoralists that probably derived from west-to-east migration from Iberia, although two later Balearic individuals had less ancestry from steppe pastoralists. In Sicily, steppe pastoralist ancestry arrived by ~2200 BC, in part from Iberia; Iranian-related ancestry arrived by the mid-second millennium BC, contemporary to its previously documented spread to the Aegean; and there was large-scale population replacement after the Bronze Age. In Sardinia, nearly all ancestry derived from the island's early farmers until the first millennium BC, with the exception of an outlier from the third millennium BC, who had primarily North African ancestry and who-along with an approximately contemporary Iberian-documents widespread Africa-to-Europe gene flow in the Chalcolithic. Major immigration into Sardinia began in the first millennium BC and, at present, no more than 56-62% of Sardinian ancestry is from its first farmers. This value is lower than previous estimates, highlighting that Sardinia, similar to every other region in Europe, has been a stage for major movement and mixtures of people.

Indexed as

AgricultureDNA, AncientGenome-Wide Association StudyAfricaAnthropologyEmigration and ImmigrationEuropeHumansIranIslandsSicilySpainDNA, Ancient

Identifiers

PMID32094539
PMCPMC7080320

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