ArticleScientific reports2020
Secondary Metabolites Profiled in Cannabis Inflorescences, Leaves, Stem Barks, and Roots for Medicinal Purposes.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
144 citing papers in PubMed, 3 syntheses or guidelines pooled it, 333 citations in OpenAlex.
- The Use ofCannabis and cannabinoid research · 2022Pooled it
- Post-Harvest Operations to Generate High-Quality Medicinal Cannabis Products: A Systemic Review.Molecules (Basel, Switzerland) · 2022Pooled it
- Optimizing Photoperiod Switch to Maximize Floral Biomass and Cannabinoid Yield inFrontiers in plant science · 2021Pooled it
- Biopesticidal Potential of theInternational journal of molecular sciences · 2026Article
- Bioactive Compounds and In Vitro Antibacterial Activity of Hemp Leaves and Inflorescences as Potential Functional Feed Ingredients for Canine Nutrition.Animals : an open access journal from MDPI · 2026Article
- Back to the roots: Cannabis sativa L. root metabolism, microbiomes, and biotechnological potential.Applied microbiology and biotechnology · 2026Review
- Exploring the impact of light spectra on growth: unveiling the role of LED light in modulating phytochemical responses of feverfew (Tanacetum parthenium L.).BMC plant biology · 2026Article
- Characterizing the effect of short wavelengths on the floral flavonoid metabolome of medicinal cannabis using a comparative computational metabolomics workflow.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- The toxicology of orally administered ΔToxicology reports · 2026Article
- Nutritive Value and Cannabinoid Potency of Diverse Hemp (Journal of agricultural and food chemistry · 2026Article
- Prenylated apigenin derivatives from Cannabis sativa L.: isolation, biosynthesis, and anti-inflammatory properties.Journal of cannabis research · 2026Article
- Cannabis: from crop to shop-some insights about stability to access quality control.Journal of cannabis research · 2026Review
- Drought stress inFrontiers in plant science · 2026Review
- Article
- Vegetative and reproductive stage lighting interactions on flower yield, water use efficiency, terpenes, and cannabinoids of Cannabis sativa.Scientific reports · 2025Article
- Spectroscopy-Based Evaluation of the Antioxidant Capacity of Hemp (International journal of molecular sciences · 2025Article
- Genotype and chemotype insights of high-THC medicinal Cannabis sativa L.: the role of SSR markers in the identification of cultivars.Journal of cannabis research · 2025Article
- Harnessing bioactive compounds from Cannabis sativa residue to improve rumen fermentation and reduce methane production: in silico, in vitro, and in situ nylon bag studies.BMC veterinary research · 2025Article
- In Vitro Exposure to Vaped Tetrahydrocannabinol IncreasesMicroorganisms · 2025Article
- Acute and Subchronic Exposure to Hemp (Pharmaceuticals (Basel, Switzerland) · 2025Article
84 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cannabis research has historically focused on the most prevalent cannabinoids. However, extracts with a broad spectrum of secondary metabolites may have increased efficacy and decreased adverse effects compared to cannabinoids in isolation. Cannabis's complexity contributes to the length and breadth of its historical usage, including the individual application of the leaves, stem barks, and roots, for which modern research has not fully developed its therapeutic potential. This study is the first attempt to profile secondary metabolites groups in individual plant parts comprehensively. We profiled 14 cannabinoids, 47 terpenoids (29 monoterpenoids, 15 sesquiterpenoids, and 3 triterpenoids), 3 sterols, and 7 flavonoids in cannabis flowers, leaves, stem barks, and roots in three chemovars available. Cannabis inflorescence was characterized by cannabinoids (15.77-20.37%), terpenoids (1.28-2.14%), and flavonoids (0.07-0.14%); the leaf by cannabinoids (1.10-2.10%), terpenoids (0.13-0.28%), and flavonoids (0.34-0.44%); stem barks by sterols (0.07-0.08%) and triterpenoids (0.05-0.15%); roots by sterols (0.06-0.09%) and triterpenoids (0.13-0.24%). This comprehensive profile of bioactive compounds can form a baseline of reference values useful for research and clinical studies to understand the "entourage effect" of cannabis as a whole, and also to rediscover therapeutic potential for each part of cannabis from their traditional use by applying modern scientific methodologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.