ArticleScientific reports2020
Low Protein-High Carbohydrate Diets Alter Energy Balance, Gut Microbiota Composition and Blood Metabolomics Profile in Young Pigs.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 49 citations in OpenAlex.
- Effects of double-low rapeseed meal on growth performance, meat quality, gut microbiota, and nitrogen excretion in Cherry Valley ducks based on low-protein dietary strategies.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Effects of Dietary Crude Protein Level on Growth Performance, Immune Function, and Serum Metabolic Profile in Weaned Piglets.Animals : an open access journal from MDPI · 2026Article
- The protective role of a moderate protein diet in ETEC-infected piglets: Optimization of growth, immunity, and microbial balance.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Effects of Reduced Crude Protein Diets with Graded Methionine Supplementation on Growth Performance, Nitrogen Utilization, and Serum Metabolomic Profiles in Growing-Finishing Pigs.Animals : an open access journal from MDPI · 2026Article
- Characterising the gut microbiome of six Australian marsupials reveals captivity constrains microbiome.Animal microbiome · 2026Article
- Increased dietary protein stimulates amino acid catabolism via the gut microbiota and secondary bile acid production.Gut microbes · 2025Article
- Increasing carbohydrates or nitrogenous compounds by cecal infusion leads to an opposite influence on colonic microbiota and host metabolism in a pig model.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Untargeted metabolomics as a tool to assess the impact of dietary approaches on pig gut health: a review.Journal of animal science and biotechnology · 2025Review
- Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model.Nutrients · 2025Article
- The composition of branched-chain amino acids modulates response to nucleotide supplementation of low-protein diets in nursery pigs.Journal of animal science · 2025Article
- Productive, Physiological, and Environmental Implications of Reducing Crude Protein Content in Swine Diets: A Review.Animals : an open access journal from MDPI · 2024Review
- Low-Protein Diets Differentially Regulate Energy Balance during Thermoneutral and Heat Stress in Cobb Broiler Chicken (International journal of molecular sciences · 2024Article
- Responses in weanling pigs fed low protein diets supplemented with dietary nucleotides.Translational animal science · 2024Article
- Fecal microbiota composition, serum metabolomics, and markers of inflammation in dogs fed a raw meat-based diet compared to those on a kibble diet.Frontiers in veterinary science · 2024Article
- Microbial signatures and enterotype clusters in fattening pigs: implications for nitrogen utilization efficiency.Frontiers in microbiology · 2024Article
- Nitrogen and energy utilization and methane emissions of sheep grazing on annual pasture vs. native pasture.Journal of animal science · 2024Article
- Recombinant Phytase Modulates Blood Amino Acids and Proteomics Profiles in Pigs Fed with Low-Protein, -Calcium, and -Phosphorous Diets.International journal of molecular sciences · 2023Article
- Dietary Isoleucine and Valine: Effects on Lipid Metabolism and Ureagenesis in Pigs Fed with Protein Restricted Diets.Metabolites · 2023Article
- Advances, Implications, and Limitations of Low-Crude-Protein Diets in Pig Production.Animals : an open access journal from MDPI · 2022Review
- Effect of Isoleucine and Added Valine on Performance, Nutrients Digestibility and Gut Microbiota Composition of Pigs Fed with Very Low Protein Diets.International journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reducing dietary crude protein (CP) beyond a certain threshold leads to poor growth performance in pigs; however, the underlying mechanisms are not well understood. Following an adaption period, thirty-seven weaned pigs were weight matched (8.41 ± 0.14 kg), housed individually and randomly assigned into three groups with different dietary CP levels: 24% CP (CON; n = 12), 18% CP (n = 12) and 12% CP (n = 13) for 28 days. The body weight was not different between the CON and 18% CP diets, but 12% CP significantly decreased body weight after day 21. Compared to the CON, pigs fed with 12% CP decreased feed intake day 17 onwards. The 12% CP diet increased the energy expenditure during week 1 compared to the CON. The 12% CP influenced starch and sucrose, nitrogen, and branched-chain amino acids metabolism pathways. The feces of pigs fed with 12% CP were less enriched in Prevotella, but had higher relative abundance of Christensenedilaceae, Aligiphilus and Algoriphagus than CON and 18% CP. Overall, reducing dietary CP by 50%, but not by 25%, significantly influenced the physiological responses in nursery pigs. The pigs fed with low or standard protein diets had differential bacterial communities in their feces as well as serum metabolomics profile.
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Registered trials
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