ArticleScientific reports2020
Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 57 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Patient Education and Duloxetine, Alone or in Combination, for Patients With Multisystem Functional Somatic Disorder
Internet-delivered Psychological Treatment of Functional Gastrointestinal Disorders - A Danish Feasibility Study
Who cites it
57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 165 citations in OpenAlex.
- Association between myalgic encephalomyelitis/chronic fatigue syndrome and irritable bowel syndrome: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Prevalence of functional disorders across Europe: a systematic review and meta-analysis.European journal of epidemiology · 2024Pooled it
- Commentary: The body embarrassed-A commentary on Černis et al. (2026) and Martinez et al. (2026).JCPP advances · 2026Article
- Insulin, Glucose and Lipid Biomarkers as Possible Risk Factors for Functional Somatic Disorder: A Five-Year Follow-Up of the DanFunD Cohort.Journal of clinical medicine · 2026Article
- Patient experiences with internet-based cognitive behavioral therapy for multi-system functional somatic disorder: A qualitative study.Internet interventions · 2026Article
- Who benefits from multidisciplinary care in functional somatic disorders? Identifying cost-effective patient selection through diagnostic classification groups.Israel journal of health policy research · 2026Article
- Clinical practice guidelines in fibromyalgia. Physiotherapists' adherence in Denmark: a cross-sectional web-based survey study.Rheumatology international · 2026Article
- Prevalence, Incidence, and Associated Conditions of Complex Regional Pain Syndrome in a Large Real-World Dataset.Journal of pain research · 2026Article
- Linking Life Aspirations to Functional Medical Conditions: A Goal Contents Theory Perspective.International journal of environmental research and public health · 2025Article
- The Gut-Brain-Immune Axis in Environmental Sensitivity Illnesses: Microbiome-Centered Narrative Review of Fibromyalgia Syndrome, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, and Multiple Chemical Sensitivity.International journal of molecular sciences · 2025Review
- The role of the gut microbiome in disorders of gut-brain interaction.The FEBS journal · 2025Review
- Healthcare use and costs of functional somatic disorder in Denmark: a population-based cohort study (DanFunD).BMJ public health · 2025Article
- Exploration of TCM Comprehensive Treatment of Irritable Bowel Syndrome Based on Pathophysiological Mechanism.International journal of general medicine · 2025Review
- Article
- Functional Neurological Disorder and Autism Spectrum Disorder: A Complex and Potentially Significant Relationship.Brain and behavior · 2024Review
- Trauma-Based Sexually Dimorphic Changes in the Connectome and Its Association with Central Sensitization Syndromes-A Systematic Review.Brain sciences · 2024Review
- The Latest Data Concerning the Etiology and Pathogenesis of Irritable Bowel Syndrome.Journal of clinical medicine · 2024Review
- Review
- Review
- Is reduced heart rate variability associated with functional somatic disorders? A cross-sectional population-based study; DanFunD.BMJ open · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prevalence of functional somatic syndromes (FSS) in the general population varies with observed overlap between syndromes. However, studies including a range of FSS are sparse. We investigated prevalence and characteristics of various FSS and the unifying diagnostic construct bodily distress syndrome (BDS), and identified mutual overlap of the FSS and their overlap with BDS. We included a stratified subsample of 1590 adults from a randomly selected Danish general population sample (n = 7493). Telephonic diagnostic interviews performed by three trained physicians were used to identify individuals with FSS and BDS. Prevalence of overall FSS was 9.3%; 3.8% for irritable bowel, 2.2% for chronic widespread pain, 6.1% for chronic fatigue, 1.5% for whiplash associated disorders, and 0.9% for multiple chemical sensitivity. Prevalence of BDS was 10.7% where 2.0% had the multi-organ type. FSS were highly overlapping with low likelihood of having a "pure" type. Diagnostic agreement of FSS and BDS was 92.0%. Multi-syndromatic FSS and multi-organ BDS were associated with female sex, poor health, physical limitations, and comorbidity. FSS are highly prevalent and overlapping, and multi-syndromatic cases are most affected. BDS captured the majority of FSS and may improve clinical management, making the distinction between multi- and mono-syndromatic patients easier.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.