Evidence map›Paper›PMID 32094358›Full record

ArticleNature communications2020

Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia.

Joseph H Marcus, Cosimo Posth, Harald Ringbauer, Luca Lai, Robin Skeates, Carlo Sidore, Jessica Beckett, Anja Furtwängler, Anna Olivieri, Charleston W K Chiang and 28 more

Abstract readHistorical Article
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Estimating human mobility in Holocene Western Eurasia with large-scale ancient genomic data.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Pooled it
  2. Article
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  6. On the Edge of Empire: Paleogenomic Insights into Roman Dacia.bioRxiv : the preprint server for biology · 2026
    Article
  7. Graph transformer for ancient ancestry inference.bioRxiv : the preprint server for biology · 2026
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  8. Article
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  11. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
    Article
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Joseph H Marcus *Department of Human Genetics, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-0923-9881
Cosimo Posth *Max Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0002-8206-3907
Harald Ringbauer *Department of Human Genetics, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-4884-9682
Luca LaiDepartment of Anthropology, University of South Florida, Tampa, FL, USA.
Robin SkeatesDepartment of Archaeology, Durham University, Durham, UK.
Carlo SidoreIstituto di Ricerca Genetica e Biomedica - CNR, Cagliari, Italy.ORCID http://orcid.org/0000-0001-7504-7477
Jessica BeckettPrivate contractor, Cagliari, Sardinia, Italy.
Anja FurtwänglerInstitute for Archaeological Sciences, University of Tübingen, Tübingen, Germany.
Anna OlivieriDipartimento di Biologia e Biotecnologie "L. Spallanzani", Università di Pavia, Pavia, Italy.ORCID http://orcid.org/0000-0002-3941-8098
Charleston W K ChiangCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-0668-7865
Hussein Al-AsadiDepartment of Statistics, University of Chicago, Chicago, IL, USA.
Kushal DeyDepartment of Statistics, University of Chicago, Chicago, IL, USA.
Tyler A JosephDepartment of Computer Science, Columbia University, New York, NY, USA.
Chi-Chun LiuDepartment of Human Genetics, University of Chicago, Chicago, IL, USA.
Clio Der SarkissianLaboratoire d'Anthropologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, Université de Toulouse 3, Toulouse, France.
Rita RadzevičiūtėMax Planck Institute for the Science of Human History, Jena, Germany.
Megan MichelMax Planck Institute for the Science of Human History, Jena, Germany.
Maria Giuseppina GradoliSchool of Archaeology and Ancient History, University of Leicester, Leicester, UK.
Patrizia MarongiuDipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy.
Salvatore RubinoDipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy.
Vittorio MazzarelloDipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy.
Daniela RovinaSoprintendenza Archeologia, belle arti e paesaggio delle province di Sassari e Nuoro, Sassari, Italy.
Alessandra La FragolaDepartamento de Geografía, Historia y Humanidades Escuela Internacional de Doctorado de la Universidad de Almería, Almería, Spain.
Rita Maria SerraDipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy.
Pasquale BandieraDipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy.ORCID http://orcid.org/0000-0002-0589-4539
Raffaella BianucciDepartment of Sciences and Technological Innovation, University of Eastern Piedmont, 15121, Alessandria, Italy.
Elisa PompianuDepartment of History, Human Sciences and Education, University of Sassari, 07100, Sassari, Italy.
Clizia MurgiaUniversitat Autònoma de Barcelona, Departament de Biologia Animal, Biologia Vegetal i Ecologia, 08193, Barcelona, Spain.
Michele GuirguisDepartment of History, Human Sciences and Education, University of Sassari, 07100, Sassari, Italy.ORCID http://orcid.org/0000-0001-9222-5124
Rosana Pla OrquinDepartment of History, Human Sciences and Education, University of Sassari, 07100, Sassari, Italy.ORCID http://orcid.org/0000-0002-6448-015X
Noreen TurossDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA, 02138, USA.ORCID http://orcid.org/0000-0002-3080-4005
Peter van DommelenJoukowsky Institute for Archaeology and the Ancient World, Brown University, Providence, RI, 02912, USA.ORCID http://orcid.org/0000-0003-0970-6651
Wolfgang HaakMax Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0003-2475-2007
David ReichDepartment of Genetics, Harvard Medical School, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0002-7037-5292
David SchlessingerLaboratory of Genetics, NIA, NIH, Baltimore, MD, USA.
Francesco CuccaIstituto di Ricerca Genetica e Biomedica - CNR, Cagliari, Italy. fcucca@uniss.it.
Johannes KrauseMax Planck Institute for the Science of Human History, Jena, Germany. krause@shh.mpg.de.ORCID http://orcid.org/0000-0001-9144-3920
John NovembreDepartment of Human Genetics, University of Chicago, Chicago, IL, USA. jnovembre@uchicago.edu.ORCID http://orcid.org/0000-0001-5345-0214

Funding

PREDOCTORAL TRAINING IN GENETICS AND REGULATIONT32GM007197 · NIGMS · UNIVERSITY OF CHICAGO · PI ROTHMAN-DENES, LUCIA B. B · 1985 to 2020
$17.0M
Aging-related Traits and Disease Risk Factors in a Sardinian Population CohortZIAAG000675 · NIA · NATIONAL INSTITUTE ON AGING · PI GOROSPE, MYRIAM · 2009 to 2021
$5.7M
Haplotype-based analysis methods for population genomicsR01HG007089 · NHGRI · UNIVERSITY OF CHICAGO · PI NOVEMBRE, JOHN · 2013 to 2017
$1.5M
Extending Tools for Visualization of Geographic Structure in Population Genomic DataR01GM132383 · NIGMS · UNIVERSITY OF CHICAGO · PI NOVEMBRE, JOHN · 2019 to 2022
$1.4M
NHGRI NIH HHS R01 HG007089NIDA NIH HHS HHSN271201100005CNIGMS NIH HHS R01 GM132383NIGMS NIH HHS T32 GM007197
6 · The paper itself

Abstract

The island of Sardinia has been of particular interest to geneticists for decades. The current model for Sardinia's genetic history describes the island as harboring a founder population that was established largely from the Neolithic peoples of southern Europe and remained isolated from later Bronze Age expansions on the mainland. To evaluate this model, we generate genome-wide ancient DNA data for 70 individuals from 21 Sardinian archaeological sites spanning the Middle Neolithic through the Medieval period. The earliest individuals show a strong affinity to western Mediterranean Neolithic populations, followed by an extended period of genetic continuity on the island through the Nuragic period (second millennium BCE). Beginning with individuals from Phoenician/Punic sites (first millennium BCE), we observe spatially-varying signals of admixture with sources principally from the eastern and northern Mediterranean. Overall, our analysis sheds light on the genetic history of Sardinia, revealing how relationships to mainland populations shifted over time.

Indexed as

DNA, AncientHuman MigrationModels, GeneticArchaeologyBody RemainsChromosomes, Human, XChromosomes, Human, YDatasets as TopicDNA, MitochondrialFemaleGenetics, PopulationHistory, 15th CenturyHistory, 16th CenturyHistory, 17th CenturyHistory, 18th CenturyHistory, 19th CenturyDNA, AncientDNA, Mitochondrial

Identifiers

PMID32094358
PMCPMC7039977

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.