Evidence map›Paper›PMID 32094318›Full record

ReviewThe American journal of case reports2020

Burkitt Leukemia Presenting as Acute Appendicitis: A Case Report and Literature Review.

Alexander H Mimery, Joe Jabbour, Blake Sykes, Ewan MacDermid, Mohamed Al-Askari, Stefaan De Clercq

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in The American journal of case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexander H MimeryDepartment of Surgery, Gladstone Hospital, Gladstone, Queensland, Australia.
Joe JabbourDepartment of Surgery, Gladstone Hospital, Gladstone, Queensland, Australia.
Blake SykesDepartment of Surgery, Gladstone Hospital, Gladstone, Queensland, Australia.
Ewan MacDermidDepartment of Colorectal Surgery, Royal North Shore Hospital, Sydney, New South Wales, Australia.
Mohamed Al-AskariDepartment of Surgery, Gladstone Hospital, Gladstone, Queensland, Australia.
Stefaan De ClercqDepartment of Surgery, Gladstone Hospital, Gladstone, Queensland, Australia.
Royal North Shore Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<strong>BACKGROUND</strong> Appendicitis is the most common cause of an acute abdomen. Approximately 1% of appendicectomies will have an incidental finding of an appendiceal neoplasm. A primary appendiceal lymphoma is extremely rare, and is found in 0.015% of all appendiceal specimens. Burkitt lymphoma is an aggressive B cell lymphoma characterized by translocation and dysregulation of the c-Myc gene. Burkitt leukemia is considered to be an alternative manifestation of the same pathology, and is defined by the presence of >25% Burkitt blasts within the bone marrow. The treatment approaches for Burkitt leukemia/lymphoma are similar. <strong>CASE REPORT</strong> A 6-year old girl presented with a history, examination, and radiological imaging consistent with acute appendicitis. An inflamed, edematous appendix was identified intraoperatively, and a cecectomy was performed. Histopathological investigations demonstrated Burkitt leukemia with isolated extra-nodal involvement of the appendix. The patient was subsequently started on a multi-agent steroid and chemotherapy regimen. A literature review was performed, identifying cases of Burkitt leukemia/lymphoma presenting as appendicitis. <strong>CONCLUSIONS</strong> This case highlights the importance of clinical vigilance and routine specimen histopathology review, and explores key management considerations associated with the incidental diagnosis of Burkitt leukemia/lymphoma.

Indexed as

Abdomen, AcuteAntineoplastic Combined Chemotherapy ProtocolsAppendectomyAppendiceal NeoplasmsBurkitt LymphomaChildDiagnosis, DifferentialFemaleHumansSteroidsSteroids

Identifiers

PMID32094318
PMCPMC7038641
OpenAlexW3003952493

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.