Evidence map›Paper›PMID 32094258›Full record

ReviewInfection and immunity2020

Staphylococcus aureus Osteomyelitis: Bone, Bugs, and Surgery.

Kenneth L Urish, James E Cassat

Abstract readReview
In one paragraph

Review in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. International journal of molecular sciences · 2023
    Pooled it
  4. Review
  5. Article
  6. Article
  7. Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026
    Review
  8. Discovery of a Thermostable Nigerose Phosphorylase for the Efficient Chemoenzymatic Radiosynthesis of aJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Osteomyelitis.Nature reviews. Disease primers · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kenneth L UrishArthritis and Arthroplasty Design Group, The Bone and Joint Center, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA ken.urish@pitt.edu jim.cassat@vanderbilt.edu.
James E CassatDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA ken.urish@pitt.edu jim.cassat@vanderbilt.edu.

Funding

Institutional Career Development CoreKL2TR001856 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, KRISTIN N, RUBIO, DORIS M · 2016 to 2025
$13.8M
Defining the impact of host factors on the molecular architecture and bacterial physiology of Staphylococcus aureus abscessesR01AI145992 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E, SKAAR, ERIC P · 2020 to 2024
$3.8M
The impact of hypoxia on Staphylococcus aureus metabolism and virulence during osteomyelitisR01AI132560 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E · 2017 to 2021
$1.9M
Host-pathogen interactions during osteomyelitisK08AI113107 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E · 2014 to 2018
$885k
Biofilm antibiotic tolerance in periprosthetic joint infectionK08AR071494 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI URISH, KENNETH L · 2017 to 2021
$831k
NCATS NIH HHS KL2 TR001856NIAID NIH HHS K08 AI113107NIAID NIH HHS R01 AI132560NIAID NIH HHS R01 AI145992NIAMS NIH HHS K08 AR071494
6 · The paper itself

Abstract

Osteomyelitis, or inflammation of bone, is most commonly caused by invasion of bacterial pathogens into the skeleton. Bacterial osteomyelitis is notoriously difficult to treat, in part because of the widespread antimicrobial resistance in the preeminent etiologic agent, the Gram-positive bacterium

Indexed as

AnimalsBiopsyCombined Modality TherapyDisease ManagementDisease SusceptibilityHumansOsteomyelitisResearchStaphylococcal InfectionsStaphylococcus aureusSymptom Assessmentboneepidemiologyhost-pathogen interactionsmusculoskeletal infectionosteoimmunologyosteomyelitispathogenesisStaphylococcus aureustreatmentvirulence

Identifiers

PMID32094258
PMCPMC7309607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.