Evidence map›Paper›PMID 32094256›Full record

ArticleInfection and immunity2020

Chlamydia trachomatis Oligopeptide Transporter Performs Dual Functions of Oligopeptide Transport and Peptidoglycan Recycling.

Raghuveer Singh, George Liechti, Jessica A Slade, Anthony T Maurelli

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Infection and immunity · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Metabolism and physiology of pathogenic bacterial obligate intracellular parasites.Frontiers in cellular and infection microbiology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Transcriptome reveals the role of theFrontiers in microbiology · 2023
    Article
  13. Expression Level of thePolish journal of microbiology · 2022
    Article
  14. Article
  15. Article
  16. Localized Peptidoglycan Biosynthesis inFrontiers in microbiology · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Raghuveer SinghEmerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-0440-4147
George LiechtiDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.ORCID 0000-0003-3028-8474
Jessica A SladeEmerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.
Anthony T MaurelliEmerging Pathogens Institute, University of Florida, Gainesville, Florida, USA amaurelli@phhp.ufl.edu.ORCID 0000-0002-4788-6166
University of Florida · USUniformed Services University of the Health Sciences · US

Funding

Peptidoglycan Assembly, Degradation, and Function in Pathogenic ChlamydiaR01AI123300 · NIAID · UNIVERSITY OF FLORIDA · PI MAURELLI, ANTHONY T · 2017 to 2021
$1.9M
NIAID NIH HHS R01 AI123300
6 · The paper itself

Abstract

Peptidoglycan, the sugar-amino acid polymer that composes the bacterial cell wall, requires a significant expenditure of energy to synthesize and is highly immunogenic. To minimize the loss of an energetically expensive metabolite and avoid host detection, bacteria often recycle their peptidoglycan, transporting its components back into the cytoplasm, where they can be used for subsequent rounds of new synthesis. The peptidoglycan-recycling substrate binding protein (SBP) MppA, which is responsible for recycling peptidoglycan fragments in

Indexed as

Amino AcidsBacterial ProteinsBiological TransportCarrier ProteinsCell Line, TumorCell WallChlamydia InfectionsChlamydia trachomatisCytosolEscherichia coliGenes, BacterialHeLa CellsHumansImmunity, InnateMembrane Transport ProteinsOligopeptidesAmino AcidsBacterial ProteinsCarrier ProteinsMembrane Transport ProteinsOligopeptidesPeptidoglycanChlamydia trachomatisimmune dampeningmetabolismnutrient acquisitionoligopeptide transport (Opp)pathoadaptationpeptidoglycan recyclingtri-DAPtriornithine

Identifiers

PMID32094256
PMCPMC7171251
OpenAlexW3007432611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.