Evidence map›Paper›PMID 32094253›Full record

ArticleInfection and immunity2020

Matrix Metalloproteinases Expressed in Response to Bacterial Vaginosis Disrupt the Endocervical Epithelium, Increasing Transmigration of HIV.

Michelle D Cherne, Amy L Cole, Lisa Newberry, Mary Schmidt-Owens, Michael Deichen, Alexander M Cole

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. HIV Transmission and Immunology of the Male Reproductive Tract.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  3. Anaerobe-Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
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  11. Article
  12. Article
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  14. Review
  15. Semen: A modulator of female genital tract inflammation and a vector for HIV-1 transmission.American journal of reproductive immunology (New York, N.Y. : 1989) · 2021
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michelle D CherneLaboratory of Innate Host Defense, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Amy L ColeLaboratory of Innate Host Defense, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Lisa NewberryStudent Health Services, University of Central Florida, Orlando, Florida, USA.
Mary Schmidt-OwensStudent Health Services, University of Central Florida, Orlando, Florida, USA.
Michael DeichenStudent Health Services, University of Central Florida, Orlando, Florida, USA.
Alexander M ColeLaboratory of Innate Host Defense, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA acole@ucf.edu.
University of Central Florida · US

Funding

Bacterial vaginosis induces matrix metalloproteinases that enhance HIV infection in womenR21AI147686 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI COLE, ALEXANDER MICHAEL · 2020 to 2021
$408k
NIAID NIH HHS R21 AI147686
6 · The paper itself

Abstract

Bacterial vaginosis (BV), a disorder of the female reproductive tract (FRT) in which a healthy

Indexed as

Cell MovementPermeabilityCells, CulturedEndometriumEpitheliumFemaleHIV-1HumansLymphocytesMatrix MetalloproteinasesModels, TheoreticalVaginosis, BacterialMatrix Metalloproteinasesbacterial vaginosisfemale reproductive tracthuman immunodeficiency virusmatrix metalloproteinasesmucosal immunity

Identifiers

PMID32094253
PMCPMC7093129
OpenAlexW3004886348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.