Evidence map›Paper›PMID 32094220›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2020

Increasing uptake of hepatitis C virus infection case-finding, testing, and treatment in primary care: evaluation of the HepCATT (Hepatitis C Assessment Through to Treatment) trial.

Jeremy Horwood, Clare Clement, Kirsty Roberts, Cherry-Ann Waldron, William L Irving, John Macleod, Mathew Hickman

Open access · hybridAbstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Implementation of the CHIldren with acute COugh (CHICO) intervention to improve antibiotics management: a qualitative study in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Trial
  3. Trial
  4. Article
  5. Article
  6. Pilot postal birth cohort hepatitis C virus screening in UK primary care: HepCAPP study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jeremy HorwoodCentre for Academic Primary Care/Bristol Randomised Trials Collaboration, Bristol Trials Centre, Population Health Sciences, Bristol Medical School, University of Bristol; National Institute for Health Research, Applied Research Collaboration West (NIHR ARC West) at University Hospitals Bristol NHS Foundation Trust, Bristol.
Clare ClementCentre for Academic Primary Care/Bristol Randomised Trials Collaboration, Bristol Trials Centre, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol.
Kirsty RobertsCentre for Academic Primary Care/Bristol Randomised Trials Collaboration, Bristol Trials Centre, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol.
Cherry-Ann WaldronCentre for Trials Research, Cardiff University, Cardiff.
William L IrvingNIHR Nottingham Digestive Diseases Biomedical Research Unit, University Hospital Nottingham, Nottingham.
John MacleodCentre for Academic Primary Care, Population Health Sciences, Bristol Medical School, University of Bristol; NIHR ARC West at University Hospitals Bristol NHS Foundation Trust, Bristol.
Mathew HickmanCentre for Academic Primary Care, Population Health Sciences, Bristol Medical School, University of Bristol; National Institute for Health Research, Health Protection Research Unit in Evaluation of Interventions, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol.
University of Bristol · GBCardiff University · GB

Funding

Department of Health RP-DG-0610-10055Medical Research Council MR/K025643/1
6 · The paper itself

Abstract

backgroundHepatitis C virus (HCV) infection is a key cause of liver disease but can be cured in more than 95% of patients. Around 70 000 people in England may have undiagnosed HCV infection and many more will not have been treated. Interventions to increase case-finding in primary care are likely to be cost-effective; however, evidence of effective interventions is lacking. The Hepatitis C Assessment Through to Treatment (HepCATT) trial assessed whether a complex intervention in primary care could increase case-finding, testing, and treatment of HCV.

aimTo investigate the feasibility and acceptability of the HepCATT intervention. DESIGN AND

settingA qualitative study with primary care practice staff from practices in the south west of England taking part in the HepCATT trial.

methodSemi-structured interviews were carried out with GPs, nurses, and practice staff to ascertain their views of the HepCATT intervention at least 1 month after implementing the intervention in their practice. Normalisation process theory, which outlines the social processes involved in intervention implementation, informed thematic data analysis.

resultsParticipants appreciated the HepCATT intervention for increasing knowledge and awareness of HCV. Although some initial technical difficulties were reported, participants saw the benefits of using the audit tool to systematically identify patients with HCV infection risk factors and found it straightforward to use. Participants valued the opportunity to discuss HCV testing with patients, especially those who may not have been previously aware of HCV risk. Future implementation should consider fully integrating software systems and additional resources to screen patient lists and conduct tests.

conclusionWhen supported by a complex intervention, primary care can play a crucial role in identifying and caring for patients with HCV infection, to help stem the HCV epidemic, and prevent HCV-related illness.

Indexed as

HepacivirusHepatitis CPrimary Health CareCost-Benefit AnalysisEnglandHumanshepatitis Cprimary carequalitative researchrandomised controlled trialscreening

Identifiers

PMID32094220
PMCPMC7041637
OpenAlexW3008650834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.