Evidence map›Paper›PMID 32094196›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Safeguarding intestine cells against enteropathogenic

Jiaming Qiu, Yunyu Nie, Yuan Zhao, Yu Zhang, Linting Li, Rui Wang, Miaomiao Wang, Sheng Chen, Jianhao Wang, Yong-Qiang Li and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  5. Nck adaptors at a glance.Journal of cell science · 2021
    Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jiaming QiuDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Yunyu NieDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Yuan ZhaoSchool of Pharmaceutical Engineering and Life Science, Changzhou University, Changzhou, Jiangsu 213164, China.
Yu ZhangDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Linting LiDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Rui WangDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Miaomiao WangDepartment of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong SAR, China.
Sheng ChenDepartment of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong SAR, China.ORCID 0000-0003-3526-7808
Jianhao WangSchool of Pharmaceutical Engineering and Life Science, Changzhou University, Changzhou, Jiangsu 213164, China; minuswan@163.com lyq@suda.edu.cn jiangxia@cuhk.edu.hk.
Yong-Qiang LiSchool of Physics, Shandong University, Jinan, Shandong 250100, China minuswan@163.com lyq@suda.edu.cn jiangxia@cuhk.edu.hk.
Jiang XiaDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China; minuswan@163.com lyq@suda.edu.cn jiangxia@cuhk.edu.hk.ORCID 0000-0001-8112-7625
Chinese University of Hong Kong · HKChangzhou University · CNCity University of Hong Kong · HKShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A critical problem in the fight against bacterial infection is the rising rates of resistance and the lack of new antibiotics. The discovery of new targets or new antibacterial mechanisms is a potential solution but is becoming more difficult. Here we report an antibacterial mechanism that safeguards intestine cells from enteropathogenic

Indexed as

ActinsAdaptor Proteins, Signal TransducingAnimalsAntimicrobial Cationic PeptidesCaco-2 CellsEnteropathogenic Escherichia coliEscherichia coli InfectionsEscherichia coli ProteinsHost-Pathogen InteractionsHumansIntestinal MucosaMiceMice, Inbred C57BLOncogene ProteinsProtein BindingReceptors, Cell SurfaceActinsAdaptor Proteins, Signal TransducingAntimicrobial Cationic PeptidesEscherichia coli ProteinsNck proteinOncogene ProteinsReceptors, Cell SurfaceTir protein, E colibacterial infectionEPECNckpeptide inhibitorsite-specific protein reaction

Identifiers

PMID32094196
PMCPMC7071885
OpenAlexW3007304262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.