Evidence map›Paper›PMID 32094179›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Evaluation of a concerted vs. sequential oxygen activation mechanism in α-ketoglutarate-dependent nonheme ferrous enzymes.

Serra Goudarzi, Shyam R Iyer, Jeffrey T Babicz, James J Yan, Günther H J Peters, Hans E M Christensen, Britt Hedman, Keith O Hodgson, Edward I Solomon

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Elucidating the Role of OACS environmental Au · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Spectroscopic and in vitro Investigations of FeChembiochem : a European journal of chemical biology · 2022
    Review
  8. Mechanisms of OBiochemistry · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Serra GoudarziDepartment of Chemistry, Stanford University, Stanford, CA 94305.
Shyam R IyerDepartment of Chemistry, Stanford University, Stanford, CA 94305.
Jeffrey T BabiczDepartment of Chemistry, Stanford University, Stanford, CA 94305.
James J YanDepartment of Chemistry, Stanford University, Stanford, CA 94305.ORCID 0000-0001-5516-3446
Günther H J PetersDepartment of Chemistry, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.ORCID 0000-0001-9754-2663
Hans E M ChristensenDepartment of Chemistry, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Britt HedmanStanford Synchrotron Radiation Lightsource, Stanford Linear Accelerator Center (SLAC) National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025.
Keith O HodgsonDepartment of Chemistry, Stanford University, Stanford, CA 94305.
Edward I SolomonDepartment of Chemistry, Stanford University, Stanford, CA 94305; solomone@stanford.edu.ORCID 0000-0003-0291-3199
Fermi National Accelerator Laboratory · USStanford University · USTechnical University of Denmark · DK

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
SPECTROSCOPIC STUDIES OF NONHEME IRON ENZYMESR01GM040392 · NIGMS · STANFORD UNIVERSITY · PI SOLOMON, EDWARD I · 1988 to 2021
$8.6M
NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM040392
6 · The paper itself

Abstract

Determining the requirements for efficient oxygen (O

Indexed as

Enzyme ActivationIntramolecular TransferasesIronKetoglutaric AcidsNonheme Iron ProteinsOxidation-ReductionPenicillin-Binding ProteinsPenicillin GReactive Oxygen SpeciesSubstrate Specificitydeacetoxycephalosporin C synthetaseIntramolecular TransferasesIronKetoglutaric AcidsNonheme Iron ProteinsPenicillin-Binding ProteinsPenicillin GReactive Oxygen Speciesconcerted mechanismmetalloenzymesoxygen activationoxygenase chemistry

Identifiers

PMID32094179
PMCPMC7071927
OpenAlexW3008312487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.