Evidence map›Paper›PMID 32094161›Full record

ArticleJournal of bacteriology2020

A Membrane-Bound Transcription Factor is Proteolytically Regulated by the AAA+ Protease FtsH in Staphylococcus aureus.

Won-Sik Yeo, Chiamara Anokwute, Philip Marcadis, Marcus Levitan, Mahmoud Ahmed, Yeun Bae, Kyeongkyu Kim, Tatiana Kostrominova, Qian Liu, Taeok Bae

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Effect of Essential Oil fromAntibiotics (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Antagonism of RhizospherePathogens (Basel, Switzerland) · 2022
    Article
  7. Article
  8. StaphylococcalInternational journal of molecular sciences · 2022
    Article
  9. Review
  10. Article
  11. Ftsh Sensitizes Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2021
    Article
  12. Characterization of FtsH Essentiality inFrontiers in genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Won-Sik YeoDepartment of Microbiology and Immunology, Indiana University School of Medicine-Northwest, Gary, Indiana, USA.
Chiamara AnokwuteDepartment of Biology, Indiana University Northwest, Gary, Indiana, USA.
Philip MarcadisDepartment of Microbiology and Immunology, Indiana University School of Medicine-Northwest, Gary, Indiana, USA.
Marcus LevitanDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Mahmoud AhmedDepartment of Biology, Indiana University Northwest, Gary, Indiana, USA.
Yeun BaeDepartment of Psychology, Indiana University, Bloomington, Indiana, USA.
Kyeongkyu KimDepartment of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, South Korea.
Tatiana KostrominovaDepartment of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine-Northwest, Gary, Indiana, USA.
Qian LiuDepartment of Laboratory Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China qq2005011@163.com tbae@iun.edu.
Taeok BaeDepartment of Microbiology and Immunology, Indiana University School of Medicine-Northwest, Gary, Indiana, USA qq2005011@163.com tbae@iun.edu.ORCID 0000-0002-0576-2851
Indiana University Northwest · USIndiana University Bloomington · USShanghai Jiao Tong University · CNSungkyunkwan University · KR

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
NCATS NIH HHS UL1 TR002529
6 · The paper itself

Abstract

In bacteria, chromosomal DNA resides in the cytoplasm, and most transcription factors are also found in the cytoplasm. However, some transcription factors, called membrane-bound transcription factors (MTFs), reside in the cytoplasmic membrane. Here, we report the identification of a new MTF in the Gram-positive pathogen

Indexed as

AnimalsATPases Associated with Diverse Cellular ActivitiesBacterial ProteinsCell MembraneFemaleGene Expression Regulation, BacterialHumansMaleMiceMice, Inbred C57BLProteolysisStaphylococcal InfectionsStaphylococcus aureusTranscription FactorsATPases Associated with Diverse Cellular ActivitiesBacterial ProteinsTranscription Factorsmembrane localizationproteasesStaphylococcus aureustranscription factors

Identifiers

PMID32094161
PMCPMC7148131
OpenAlexW3007342366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.