ArticleThe Journal of pediatrics2020
Gestational Age, Perinatal Characteristics, and Autism Spectrum Disorder: A Birth Cohort Study.
Article in The Journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Effect of cesarean section on the risk of autism spectrum disorders/attention deficit hyperactivity disorder in offspring: a meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- The prevalence and profile of autism in individuals born preterm: a systematic review and meta-analysis.Journal of neurodevelopmental disorders · 2021Pooled it
- Association Between Gestational Weight Gain and Autism Spectrum Disorder in Offspring: A Meta-Analysis.Obesity (Silver Spring, Md.) · 2020Pooled it
- Exploring Parental Factors in Autism Spectrum Disorder Risk: A Case-Control Study.Maternal and child health journal · 2026Article
- Article
- Role of soluble alpha-klotho as a novel biomarker for characterizing children with autism spectrum disorder in Kurdistan, Iraq.World journal of clinical pediatrics · 2026Article
- Biopsychosocial factors during pregnancy and their implications for autism spectrum disorder: a scoping review.BMC pediatrics · 2026Article
- Prenatal Diabetes and Obesity: Implications for Autism Spectrum Disorders in Offspring - A Comprehensive Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Incidence and risk factors for autism spectrum disorder among infants born <29 weeks' gestation.Paediatrics & child health · 2022Article
- Defective placentation syndromes and autism spectrum disorder in the offspring: population-based cohort and sibling-controlled studies.European journal of epidemiology · 2022Article
- Perinatal Factors in Newborn Are Insidious Risk Factors for Childhood Autism Spectrum Disorders: A Population-based Study.Journal of autism and developmental disorders · 2022Article
- Nutritional Management of Moderate- and Late-Preterm Infants Commenced on Intravenous Fluids Pending Mother's Own Milk: Cohort Analysis From the DIAMOND Trial.Frontiers in pediatrics · 2022Article
- Association between small for gestational age and risk of autism spectrum disorders: a meta-analysis.Clinical and experimental pediatrics · 2021Article
- Preterm or Early Term Birth and Risk of Autism.Pediatrics · 2021Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveTo determine how gestational age relates to research-identified autism spectrum disorder (ASD-R) in the context of perinatal risk factors. STUDY
designThis is a population-based cohort study using the 1994-2000 Olmsted County Birth Cohort. Children included were born and remained in Olmsted County after age 3 years. ASD-R status was determined from signs and symptoms abstracted from medical and educational records. Cox proportional hazards models were fit to identify associations between perinatal characteristics and ASD-R.
resultsThe incidence of preterm birth (<37 weeks' gestation) was 8.6% among 7876 children. The cumulative incidence of ASD-R was 3.8% (95% CI 3.3-4.2) at 21 years of age. Compared with children born at full term, the risk of ASD-R appeared to be increased for children born preterm with unadjusted hazard ratios (HRs) of 2.62 (95% CI 0.65-10.57), 1.68 (95% CI 0.54-5.29), and 1.60 (95% CI 1.06-2.40) for children born extremely preterm, very preterm, and moderate-to-late preterm, respectively. In a multivariable model adjusted for perinatal characteristics, the associations were attenuated with adjusted HRs of 1.75 (95% CI 0.41-7.40), 1.24 (95% CI 0.38-4.01), and 1.42 (95% CI 0.93-2.15), for children born extremely preterm, very preterm, and moderate-to-late preterm, respectively. Among children with maternal history available (N = 6851), maternal psychiatric disorder was associated with ASD-R (adjusted HR 1.73, 95% CI 1.24-2.42).
conclusionsThe increased risk of ASD-R among children born preterm relative to children born full term was attenuated by infant and maternal characteristics.
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Registered trials
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