Evidence map›Paper›PMID 32093784›Full record

ArticleBMC research notes2020

Bactericidal activity of hexylresorcinol lozenges against oropharyngeal organisms associated with acute sore throat.

Derek Matthews, Oluwajoba Adegoke, Adrian Shephard

Abstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Are Non-animal Systemic Safety Assessments Protective? A Toolbox and Workflow.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Article
  8. 4-Hexylresorcinol: pharmacologic chaperone and its application for wound healing.Maxillofacial plastic and reconstructive surgery · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Derek MatthewsReckitt Benckiser Healthcare International Ltd, 103-105 Bath Road, Slough, Berkshire, SL1 3UH, UK. derek.matthews@rb.com.ORCID http://orcid.org/0000-0002-5898-1417
Oluwajoba AdegokeReckitt Benckiser Healthcare UK Ltd, Dansom Lane, Hull, HU8 7DS, UK.
Adrian ShephardReckitt Benckiser Healthcare International Ltd, 103-105 Bath Road, Slough, Berkshire, SL1 3UH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFor the majority of people with acute sore throat, over-the-counter treatments represent the primary option for symptomatic relief. This study evaluated the in vitro bactericidal activity of lozenges containing the antiseptic hexylresorcinol against five bacteria associated with acute sore throat: Staphylococcus aureus, Streptococcus pyogenes, Moraxella catarrhalis, Haemophilus influenzae and Fusobacterium necrophorum.

resultsHexylresorcinol 2.4 mg lozenges were dissolved into 5 mL of artificial saliva medium. Inoculum cultures were prepared in triplicate for each test organism to give an approximate population of 10

Indexed as

Administration, OralAnti-Infective Agents, LocalBacterial InfectionsBacterial LoadCommon ColdFusobacterium necrophorumHaemophilus influenzaeHexylresorcinolHumansMicrobial Sensitivity TestsMoraxella catarrhalisOropharynxStaphylococcus aureusStreptococcus pyogenesTime FactorsAnti-Infective Agents, LocalHexylresorcinolAntibacterial agentsAntisepticBacterial infectionBactericidalPharyngitisSore throat

Identifiers

PMID32093784
PMCPMC7041292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.