Evidence map›Paper›PMID 32093763›Full record

GuidelineCritical care (London, England)2020

International evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).

Yogen Singh, Cecile Tissot, María V Fraga, Nadya Yousef, Rafael Gonzalez Cortes, Jorge Lopez, Joan Sanchez-de-Toledo, Joe Brierley, Juan Mayordomo Colunga, Dusan Raffaj and 9 more

5 registry-linked trialsOpen access · goldAbstract readPractice Guideline
In one paragraph

Guideline in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 296 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
296citing papers in PubMed, 10 pooled it
42.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04660448 completednot on this map

Lung Ultrasound Score and Pediatric Intensive Care Outcomes: a Prospective Observational Multicenter Study

Typeobservational_patient_registrySponsorFundación para la Investigación Biosanitaria del Principado de AsturiasRan2020 to 2021Enrolled650ConditionsLung Injury, Extravascular Lung Water, Pulmonary Edema, Acute Respiratory Distress SyndromeArmsBedside lung ultrasound examination
NCT06144463 nacompletednot on this mapstarted 2022, after this paper: background citation

Study on the Application Value of Fluid Resuscitation Guided by Lung Ultrasound in Neonatal Septic Shock

TypeinterventionalSponsorGuangdong Second Provincial General HospitalRan2022 to 2023Enrolled72ConditionsSeptic ShockArmslung ultrasound-guided fluid resuscitation
NCT06839963 completednot on this mapstarted 2025, after this paper: background citation

Validation of the Kinshasa Lung Ultrasound Approach for the Narrowing of Differential Diagnosis in Children Admitted With Acute Respiratory Symptoms in Low-resource Settings

TypeobservationalSponsorUniversity of OxfordRan2025 to 2025Enrolled178ConditionsRespiratory Disease, Children, Only
NCT06880016 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of Serial Lung Ultrasound Data After Surfactant Treatments Applied With Different Methods in Preterm Babies

TypeinterventionalSponsorKonya City HospitalRan2024 to 2027Enrolled68ConditionsNewborn Complication, Respiratory Distress Syndrome, NewbornArmsEvaluation of serial lung ultrasound data after ENSURE surfactant treatments, Evaluation of serial lung ultrasound data after LISA surfactant treatments
NCT07273643 recruitingnot on this mapstarted 2026, after this paper: background citation

Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and Mortality

Typeobservational_patient_registrySponsorUniversity Hospital, MontpellierRan2026 to 2027Enrolled30ConditionsIntraventricular Hemorrhage, Pulmonary Hemorrhage, Death, ELGAN (22-28SA)ArmsVenous Cord blood sample, Arterial cord blood sample
3 · Its place in the literature

Who cites it

296 citing papers in PubMed, 10 syntheses or guidelines pooled it, 592 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Characteristics of scores used for quantitative lung ultrasound in neonates: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  7. Pooled it
  8. [Clinical practice guidelines for the diagnosis and treatment of anemia of prematurity (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Guideline
  9. Guideline
  10. Pooled it
  11. Trial
  12. Real-time ultrasound to assess the umbilical catheter position in neonates: a randomized, controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Interpretation of Lung Ultrasound in POCUS.Indian journal of pediatrics · 2026
    Review
  20. Review

236 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 7 countries.

Yogen Singh *Department of Paediatrics - Neonatology and Paediatric Cardiology, Cambridge University Hospitals and University of Cambridge School of Clinical Medicine, Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK. Yogen.Singh@nhs.net.ORCID http://orcid.org/0000-0002-5207-9019
Cecile Tissot *Paediatric Cardiology, Centre de Pédiatrie, Clinique des Grangettes, Geneva, Switzerland.
María V FragaDepartment of Paediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine, Philadelphia, USA.
Nadya YousefDivision of Paediatrics and Neonatal Critical Care, APHP - Paris Saclay University Hospitals, "A. Béclère" Medical centre, Paris, France.
Rafael Gonzalez CortesDepartment of Paediatric Intensive Care, Gregorio Marañón General University Hospital, Madrid, Spain.
Jorge LopezDepartment of Paediatric Intensive Care, Gregorio Marañón General University Hospital, Madrid, Spain.
Joan Sanchez-de-ToledoDepartment of Paediatric Cardiology, Sant Joan de Déu Hospital, Barcelona, Spain.
Joe BrierleyDepartment of Paediatric Intensive Care, Great Ormond Street Hospital, London, UK.
Juan Mayordomo ColungaDepartment of Paediatric Intensive Care, Hospital Universitario Central de Asturias, Oviedo. CIBER-Enfermedades Respiratorias. Instituto de Salud Carlos III, Madrid. Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.
Dusan RaffajDepartment of Paediatric Intensive Care, Nottingham University Hospitals, Nottingham, UK.
Eduardo Da CruzDepartment of Paediatric and Cardiac Intensive Care, Children's Hospital Colorado, Aurora, USA.
Philippe DurandDivision of Paediatric Critical Care, APHP - Paris Saclay University Hospitals, "Kremlin Bicetre" Medical Centre, Paris, France.
Peter KenderessyDepartment of Paediatric Anaesthesia and Intensive Care, Children's Hospital Banska Bystrica, Banska Bystrica, Slovakia.
Hans-Joerg LangDepartment of Paediatrics, Medicins Sans Frontieres (Suisse), Geneva, Switzerland.
Akira NishisakiDepartment of Anaesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and Perelman School of Medicine, Philadelphia, USA.
Martin C KneyberDepartment of Paediatrics, Division of Paediatric Critical Care Medicine, Beatrix Children's Hospital Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Pierre TissieresDivision of Paediatric Critical Care, APHP - Paris Saclay University Hospitals, "Kremlin Bicetre" Medical Centre, Paris, France.
Thomas W ConlonDepartment of Anaesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and Perelman School of Medicine, Philadelphia, USA.
Daniele De LucaDivision of Paediatrics and Neonatal Critical Care, APHP - Paris Saclay University Hospitals, "A. Béclère" Medical centre, Paris, France.
Children's Hospital of Philadelphia · USUniversité Paris-Saclay · FRHospital General Universitario Gregorio Marañón · ESAkadémia Umení v Banskej Bystrici · SKChildren's Hospital Colorado · USGreat Ormond Street Hospital · GBHirslanden Clinique des Grangettes · CHHospital Sant Joan de Déu Barcelona · ESInserm · FRInstituto de Salud Carlos III · ESMédecins Sans Frontières · CHNottingham University Hospitals NHS Trust · GBUniversity Medical Center Groningen · NLUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoint-of-care ultrasound (POCUS) is nowadays an essential tool in critical care. Its role seems more important in neonates and children where other monitoring techniques may be unavailable. POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC) aimed to provide evidence-based clinical guidelines for the use of POCUS in critically ill neonates and children.

methodsCreation of an international Euro-American panel of paediatric and neonatal intensivists expert in POCUS and systematic review of relevant literature. A literature search was performed, and the level of evidence was assessed according to a GRADE method. Recommendations were developed through discussions managed following a Quaker-based consensus technique and evaluating appropriateness using a modified blind RAND/UCLA voting method. AGREE statement was followed to prepare this document.

resultsPanellists agreed on 39 out of 41 recommendations for the use of cardiac, lung, vascular, cerebral and abdominal POCUS in critically ill neonates and children. Recommendations were mostly (28 out of 39) based on moderate quality of evidence (B and C).

conclusionsEvidence-based guidelines for the use of POCUS in critically ill neonates and children are now available. They will be useful to optimise the use of POCUS, training programs and further research, which are urgently needed given the weak quality of evidence available.

Indexed as

Intensive Care, NeonatalPoint-of-Care SystemsUltrasonographyCritical CareCritical IllnessHumansInfant, NewbornIntensive Care Units, NeonatalSystematic Reviews as TopicChildrenNeonatal intensive care unit (NICU)NeonatePaediatric intensive care unit (PICU)Point of care ultrasound (POCUS)Ultrasound

Identifiers

PMID32093763
PMCPMC7041196
OpenAlexW3007973847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.