ArticleLipids in health and disease2020
The sensibility of the new blood lipid indicator--atherogenic index of plasma (AIP) in menopausal women with coronary artery disease.
Article in Lipids in health and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.
- Atherogenic Index of Plasma and Coronary Artery Disease in the Adult Population: A Meta-Analysis.Frontiers in cardiovascular medicine · 2021Pooled it
- Reconceptualizing Dyslipidemia: Diversity of Lipid Imbalances and Their Clinical Implications; A Narrative Review.Health science reports · 2026Article
- Association of uric acid-to-HDL cholesterol ratio and coronary atherosclerotic heart disease in patients with and without CKD.BMC cardiovascular disorders · 2026Article
- Association between atherosclerotic index of plasma and long-term aortic-related adverse events in type B aortic dissection patients undergoing thoracic endovascular aortic repair.Cardiovascular diabetology · 2026Article
- Association of atherogenic index of plasma and cardiometabolic index with all-cause mortality and cardiovascular disease in NAFLD patients: NHANES 1999-2018.Cardiovascular diabetology · 2026Article
- Association between atherogenic index of plasma in early pregnancy and risk of preeclampsia: a multicenter cohort study.Frontiers in nutrition · 2026Article
- Association of the new TyG indicator-TyHGB with prediabetes and diabetes in middle-aged and elderly postmenopausal women: a longitudinal study.Frontiers in endocrinology · 2026Article
- Article
- Atherogenic index of plasma and subclinical vascular disease: predictive value for coronary and carotid atherosclerosis in a health screening population.Lipids in health and disease · 2025Article
- Associations between the atherogenic index of plasma and coronary heart disease in hypertensive patients: results from NHANES 2005-2018.BMC cardiovascular disorders · 2025Article
- Association between atherogenic index of plasma and incident aortic disease: a population-based prospective analysis.Open heart · 2025Observational
- Associations of atherogenic index of plasma and other nontraditional lipid parameters with the risk of coronary artery aneurysm.European journal of medical research · 2025Article
- Association Between Atherogenic Index of Plasma and Clinical Outcomes in Peritoneal Dialysis Population.Journal of clinical medicine · 2025Article
- Relationship between plasma atherogenic index and thyroid function: evidence from NHANES 2007-2012.Scientific reports · 2025Article
- Sex-specific association between atherogenic index of plasma and risk of newly diagnosed abdominal aortic aneurysm: a large population-based cohort study.European journal of medical research · 2025Article
- Association of the atherogenic index of plasma with frailty in U.S. adults: a cross-sectional study based on NHANES.Lipids in health and disease · 2025Article
- Gender-specific association between a novel atherogenic index of plasma, metabolic parameters and inflammation among obese adults.BMC endocrine disorders · 2025Article
- The relationship between the atherogenic index of plasma and postoperative myocardial injury following non-cardiac surgery under general anaesthesia: a retrospective cohort study.BMC cardiovascular disorders · 2025Article
- Sex-specific differences in the relationship between the atherogenic index and hypertension in middle-aged and elderly Chinese.Frontiers in endocrinology · 2025Article
- The correlation between neck circumference and atherogenic index of plasma with coronary heart disease.Frontiers in endocrinology · 2025Observational
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDyslipidemia is a key driver of coronary artery disease (CAD) development. This study aimed to determine whether the atherogenic index of plasma (AIP), a novel comprehensive lipid index, is an independent and reliable predictor of CAD risk in postmenopausal women.
methodsA cohort of consecutive 4644 postmenopausal women (aged 50 or above) undergoing coronary angiography (CAG) in Anzhen Hospital (Beijing, China) from January-December 2014 was included in the analysis. Of them, 3039 women were CAD patients, and 1605 were non-CAD subjects.
resultsRelative to control subjects, TG levels in CAD patients were higher and HDL-C levels were lower. In CAD patients, non-traditional lipid profile values (TC/HDL-C, AI, and AIP) were significantly elevated relative to controls. AIP was positively correlated with TC (r = 0.157), TG (r = 0.835), LDL-C (r = 0.058), non-HDL-C (r = 0.337), TC/HDL-C (r = 0.683), LDL-C/HDL-C (r = 0.437), LCI (r = 0.662), and AI (r = 0.684), and negatively correlated with HDL-C (r = - 0.682) (all P < 0.001), but was independent of age (r = - 0.022; P = 0.130) and BMI (r = 0.020, P = 0.168). Aunivariate logistic regression analysis revealed AIP to be the measured lipid parameter most closely related to CAD, and its unadjusted odds ratio was 1.824 (95% CI: 1.467-2.267, P < 0.001). After adjusting for several CAD risk factors (age, BMI, smoking, drinking, EH, DM, hyperlipidemia, and family history of CVD, AIP was still found to represent a significant CAD risk factor (OR 1.553, 95% CI: 1.234-1.955, P < 0. 001).
conclusionAIP may be a powerful independent predictor of CAD risk in Chinese Han postmenopausal women, and may be superior to the traditional lipid indices.
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