Evidence map›Paper›PMID 32093686›Full record

ArticleBMC nephrology2020

Atypical presentation of acute post-infectious glomerulonephritis in patients with sickle cell disease: report of two cases.

Precil Diego Miranda de Menezes Neves, Bernardo Vergara Reichert, Ramaiane Aparecida Bridi, Luis Yu, Cristiane Bitencourt Dias, Rafaela Brito Bezerra Pinheiro, Leonardo de Abreu Testagrossa, Lívia Barreira Cavalcante, Denise Maria Avancini Costa Malheiros, Lectícia Barbosa Jorge and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Precil Diego Miranda de Menezes NevesNephrology Division, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar, 255, 7° andar, Cerqueira Cesar, São Paulo, Brazil. precilmed61@yahoo.com.br.ORCID 0000-0003-1089-6763
Bernardo Vergara ReichertNephrology Division, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar, 255, 7° andar, Cerqueira Cesar, São Paulo, Brazil.
Ramaiane Aparecida BridiNephrology Division, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar, 255, 7° andar, Cerqueira Cesar, São Paulo, Brazil.
Luis YuNephrology Division, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar, 255, 7° andar, Cerqueira Cesar, São Paulo, Brazil.
Cristiane Bitencourt DiasNephrology Division, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar, 255, 7° andar, Cerqueira Cesar, São Paulo, Brazil.
Rafaela Brito Bezerra PinheiroPathology Division, University of São Paulo School of Medicine, São Paulo, Brazil.
Leonardo de Abreu TestagrossaPathology Division, University of São Paulo School of Medicine, São Paulo, Brazil.
Lívia Barreira CavalcantePathology Division, University of São Paulo School of Medicine, São Paulo, Brazil.
Denise Maria Avancini Costa MalheirosPathology Division, University of São Paulo School of Medicine, São Paulo, Brazil.
Lectícia Barbosa JorgeNephrology Division, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar, 255, 7° andar, Cerqueira Cesar, São Paulo, Brazil.
Viktoria WoronikNephrology Division, University of São Paulo School of Medicine, Av. Dr. Enéas de Carvalho Aguiar, 255, 7° andar, Cerqueira Cesar, São Paulo, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSickle cell disease (SCD) is a highly prevalent genetic disease worldwide. In the natural evolution of SCD, glomerular lesions can develop, presenting histopathological patterns of segmental or focal membranoproliferative glomerulosclerosis, with or without thrombotic microangiopathy. We report two cases of acute post-infectious glomerulonephritis (APIGN), with atypical presentations, in patients with SCD. CASE PRESENTATION: Case 1: An 18-year-old female with SCD presented with a 21-day history of progressive oedema, accompanied by dyspnoea, productive cough, fever, and chest pain. Blood tests showed the following: haemoglobin 6.1 g/dl; leucocytes 18,820 cells/mm

conclusionsThe presentation of the two cases reported here are not typical of SCD-related kidney injury. Analysis of the renal biopsy specimens elucidated the diagnosis, affecting the prognosis, because that of APIGN is highly favourable, unlike that of nephrotic syndrome associated with SCD glomerulopathy.

Indexed as

AdolescentAnemia, Sickle CellChildCreatinineFemaleGlomerular Filtration RateGlomerulonephritisHematuriaHumansKidneyMaleNephrotic SyndromeProteinuriaCreatinineAcute post-infectious glomerulonephritisNephrotic syndromeSickle cell anaemia

Identifiers

PMID32093686
PMCPMC7038555
OpenAlexW3012860885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.