ArticleTurkish journal of medical sciences2020
The use of prealbumin as a predictor of malnutrition in cirrhotic patients and the effect of nutritional support in patients with low prealbumin levels
Article in Turkish journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 11 citations in OpenAlex.
- Prognostic Significance of Preoperative Albumin and Prealbumin in Predicting Adverse Events After Posterior Lumbar Interbody Fusion in Elderly Patients.Clinical interventions in aging · 2026Article
- The Effect of Nutritional Education on Nutritional Status and Quality of Life in Patients with Liver Cirrhosis.Healthcare (Basel, Switzerland) · 2025Article
- Reference intervals for serum albumin, total protein, and prealbumin in healthy children in Nanning, China.Biomarkers in medicine · 2025Article
- Associations of serum high-sensitivity C-reactive protein and prealbumin with coronary vessels stenosis determined by coronary angiography and heart failure in patients with myocardial infarction.Journal of medical biochemistry · 2023Article
- Identification of predictors for the comprehensive clinical risk and severity of coronary lesions of acute coronary syndrome.Frontiers in cardiovascular medicine · 2023Article
- Case report of atypical undernutrition of hypoproteinemia type.Open life sciences · 2023Article
- Predictors of Morbidity and Mortality After Colorectal Surgery in Patients With Cirrhotic Liver Disease-A Retrospective Analysis of 54 Cases at a Tertiary Care Center.Frontiers in medicine · 2022Article
- Role of Prealbumin in Predicting the Prognosis of Severely and Critically Ill COVID-19 Patients.The American journal of tropical medicine and hygiene · 2021Observational
- Low preoperative prealbumin predicts the prevalence of complications following liver transplantation.BMC gastroenterology · 2021Article
- Preliminary Evidence for a Relationship between Elevated Plasma TNFα and Smaller Subcortical White Matter Volume in HCV Infection Irrespective of HIV or AUD Comorbidity.International journal of molecular sciences · 2021Article
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3 authors at 1 institution in 1 country.
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Abstract
Background/aim: Malnutrition is an important and commonly seen prognostic factor in patients with cirrhosis. The diagnosis of malnutrition in cirrhosis patients may be challenging, and an easily measured and widely usable marker is lacking. Prealbumin, however, is an easily measured marker. In the current study we measured prealbumin levels in cirrhotic patients with no clinically apparent malnutrition and used it as a malnutrition marker. Another aim of this study was to evaluate the effect of nutritional support on patient with low prealbumin levels. Materials and methods: Fifty-two patients with Child A and Child B cirrhosis were selected for the study. Prealbumin levels were studied, and Child and MELD scores were calculated. Patients with prealbumin levels ˂180 mg/L were considered to have malnutrition, and two different types of nutritional products were given to these patients. The patients given nutritional support were investigated a month later, and parameters were compared. Results: According to the prealbumin threshold of 180 mg/L, malnutrition frequencies were 59.3% for Child A and 95% for Child B cirrhosis. After the provision of nutritional support statistically significant improvements in albumin and INR levels were detected. In addition, the MELD score decreased; however, it was not statistically significant (P: 0.088). A statistically significant decrease in the MELD score was only obtained in patients with Child B cirrhosis (P: 0.033). When the oral replacement therapies were investigated separately, a statistically significant decrease in MELD scores was detected with product 1 (P: 0.043). Conclusion: Prealbumin can be used as an easily measured parameter for earlier detection of malnutrition in patients with cirrhosis and without clinically apparent malnutrition. Oral nutritional support, especially with products containing relatively high carbohydrate levels and low protein, may have a favorable effect on MELD scores.
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