Evidence map›Paper›PMID 32093358›Full record

ArticleInternational journal of molecular sciences2020

(+)-Limonene 1,2-Epoxide-Loaded SLNs: Evaluation of Drug Release, Antioxidant Activity, and Cytotoxicity in an HaCaT Cell Line.

Eliana B Souto, Aleksandra Zielinska, Selma B Souto, Alessandra Durazzo, Massimo Lucarini, Antonello Santini, Amélia M Silva, Atanas G Atanasov, Conrado Marques, Luciana N Andrade and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
  2. Review
  3. Encapsulation of D-limonene inCurrent research in food science · 2025
    Article
  4. Article
  5. From Extraction to Stabilization: Employing a 2Foods (Basel, Switzerland) · 2024
    Article
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  7. Article
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  12. Review
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  16. Effects of oat (Frontiers in microbiology · 2022
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 6 countries.

Eliana B SoutoFaculty of Pharmacy (FFUC), Department of Pharmaceutical Technology, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0002-9737-6017
Aleksandra ZielinskaFaculty of Pharmacy (FFUC), Department of Pharmaceutical Technology, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0003-2603-1377
Selma B SoutoDepartment of Endocrinology, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
Alessandra DurazzoCREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.ORCID 0000-0002-7747-9107
Massimo LucariniCREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Antonello SantiniDepartment of Pharmacy, University of Naples Federico II, 80131 Napoli, Italy.ORCID 0000-0001-5505-3327
Amélia M SilvaDepartment of Biology and Environment (DeBA-ECVA), University of Trás-os-Montes e Alto Douro (UTAD), Quinta de Prados, 5001-801 Vila Real, Portugal.ORCID 0000-0002-7524-9914
Atanas G AtanasovInstitute of Neurobiology, Bulgarian Academy of Sciences, 23 Acad. G. Bonchev str., 1113 Sofia, Bulgaria.ORCID 0000-0003-2545-0967
Conrado MarquesLaboratory of Nanotechnology and Nanomedicine (LNMED), Institute of Technology and Research (ITP), Av. Murilo Dantas, 300, 49010-390 Aracaju, Brazil.
Luciana N AndradeLaboratory of Nanotechnology and Nanomedicine, Institute of Technology and Research, Aracaju SE 49032-490, Brazil.
Patricia SeverinoLaboratory of Nanotechnology and Nanomedicine (LNMED), Institute of Technology and Research (ITP), Av. Murilo Dantas, 300, 49010-390 Aracaju, Brazil.ORCID 0000-0001-6527-6612
Universidade Tiradentes · BRUniversity of Coimbra · PTHospital de São João · PTUniversity of Naples Federico II · ITUniversity of Trás-os-Montes and Alto Douro · PTUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we developed a solid lipid nanoparticle (SLN) formulation with (+)-limonene 1,2-epoxide and glycerol monostearate (

Indexed as

AntioxidantsCyclohexane MonoterpenesMonoglyceridesPoloxamerCell LineDelayed-Action PreparationsHumansKeratinocytesLipid PeroxidationNanoparticlesAntioxidantsCyclohexane MonoterpenesDelayed-Action Preparationslimonene-1,2-epoxideMonoglyceridesPoloxamercytotoxicityHaCaT cell lineImwitor 900K-SLN(+)-limonene 1,2-epoxidelipid peroxidationmonoterpene

Identifiers

PMID32093358
PMCPMC7073088
OpenAlexW3006863292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.