Evidence map›Paper›PMID 32093314›Full record

ArticleInternational journal of molecular sciences2020

Characterization of Convergent Suppression by UCL-2077 (3-(Triphenylmethylaminomethyl)pyridine), Known to Inhibit Slow Afterhyperpolarization, of

Hung-Te Hsu, Yi-Ching Lo, Sheng-Nan Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Chemical modulation of Kv7 potassium channels.RSC medicinal chemistry · 2021
    Review
  8. Article
  9. Article
  10. Characterization of the Synergistic Inhibition ofInternational journal of molecular sciences · 2020
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hung-Te HsuDepartment of Anesthesia, Kaohsiung Medical University Hospital, Kaohsiung City 80756, Taiwan.
Yi-Ching LoDepartment of Pharmacology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Sheng-Nan WuDepartment of Physiology, National Cheng Kung University Medical College, Tainan 70101, Taiwan.
Kaohsiung Medical University · TWChina Medical University · TW

Funding

Kaohsiung Municipal Ta-Tung Hospital kmtth-104-051Ministry of Science and Technology, Taiwan MOST 105-2320-B-037-013-MY3National Cheng Kung University D106-35A13
6 · The paper itself

Abstract

UCL-2077 (triphenylmethylaminomethyl)pyridine) was previously reported to suppress slow afterhyperpolarization in neurons. However, the information with respect to the effects of UCL-2077 on ionic currents is quite scarce. The addition of UCL-2077 decreased the amplitude of

Indexed as

BenzylaminesCell LineERG1 Potassium ChannelGene Knockdown TechniquesHumansIon TransportPotassiumPyridinesSomatotrophs3-(triphenylmethylaminomethyl)pyridineBenzylaminesERG1 Potassium ChannelKCNH2 protein, humanPotassiumPyridinesaction currenterg-mediated potassium currentintermediate-conductance calcium-activated potassium channelsimulationUCL-2077voltage hysteresis

Identifiers

PMID32093314
PMCPMC7073080
OpenAlexW3008000934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.