Evidence map›Paper›PMID 32093298›Full record

ArticleInternational journal of molecular sciences2020

Thyrotropin-Releasing Hormone (TRH) and Somatostatin (SST), but not Growth Hormone-Releasing Hormone (GHRH) nor Ghrelin (GHRL), Regulate Expression and Release of Immune Growth Hormone (GH) from Chicken Bursal B-Lymphocyte Cultures.

Santiago Pech-Pool, Laura C Berumen, Carlos G Martínez-Moreno, Guadalupe García-Alcocer, Martha Carranza, Maricela Luna, Carlos Arámburo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Santiago Pech-PoolDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro 76230, Mexico.
Laura C BerumenPosgrado en Ciencias Químico-Biológicas, Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario, Querétaro 76010, Mexico.ORCID 0000-0001-6266-3457
Carlos G Martínez-MorenoDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro 76230, Mexico.
Guadalupe García-AlcocerPosgrado en Ciencias Químico-Biológicas, Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario, Querétaro 76010, Mexico.
Martha CarranzaDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro 76230, Mexico.
Maricela LunaDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro 76230, Mexico.ORCID 0000-0002-1409-500X
Carlos ArámburoDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro 76230, Mexico.ORCID 0000-0002-6235-8695
Universidad Nacional Autónoma de México · MXAutonomous University of Queretaro · MX

Funding

Consejo Nacional de Ciencia y Tecnología (CONACYT, México) 285004Consejo Nacional de Ciencia y Tecnología (CONACYT, México) PhD scholarship (475619) to S.P.-PPrograma de Apoyo a Proyectos de Investigación e Innovación Tecnológica de la Dirección General de Asuntos del Personal Académico (PAPIIT-DGAPA), UNAM IN201817, IN207018, IN208419Universidad Nacional Autónoma de México (UNAM) 1130-202-002
6 · The paper itself

Abstract

It is known that growth hormone (GH) is expressed in immune cells, where it exerts immunomodulatory effects. However, the mechanisms of expression and release of GH in the immune system remain unclear. We analyzed the effect of growth hormone-releasing hormone (GHRH), thyrotropin-releasing hormone (TRH), ghrelin (GHRL), and somatostatin (SST) upon GH mRNA expression, intracellular and released GH, Ser133-phosphorylation of CREB (pCREB

Indexed as

AnimalsAvian ProteinsB-LymphocytesBursa of FabriciusCell Culture TechniquesCells, CulturedChickensGhrelinGrowth HormoneGrowth Hormone-Releasing HormoneSomatostatinThyrotropin-Releasing HormoneAvian ProteinsGhrelinGrowth HormoneGrowth Hormone-Releasing HormoneSomatostatinThyrotropin-Releasing Hormonebursal B-lymphocytesbursa of fabriciusGHRHgrowth hormonesomatostatinTRH

Identifiers

PMID32093298
PMCPMC7073104
OpenAlexW3007733485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.