Evidence map›Paper›PMID 32093249›Full record

ReviewInternational journal of molecular sciences2020

Endocrine-Disrupting Chemicals in Human Fetal Growth.

Maria Elisabeth Street, Sergio Bernasconi

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06750523 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Getting Bone Health Right From the Start: Innovative Technology and New Mechanims of Mother-fetus Cross Talk for Osteopenia and Osteporosis Prevention

TypeinterventionalSponsorUniversity of ParmaRan2023 to 2025Enrolled200ConditionsLow-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population, Healthy Neonatal PopulationArmsCord blood sampling, urine sampling, Life style questionnaire
NCT07560579 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

TypeinterventionalSponsorMillion Marker Wellness, Inc.Ran2025 to 2026Enrolled226ConditionsObesity &Amp, Amp, Amp, OverweightArmsEducational curriculum, Weight loss Application, Urinary EDC metabolite testing, Siphox clinic biomarker test, Weight loss reporting
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 149 citations in OpenAlex.

  1. Pooled it
  2. Pollution, stress response, and obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Maria Elisabeth StreetDepartment of Mother and Child, 42123 Azienda USL-IRCCS di Reggio Emilia, Italy.ORCID 0000-0001-8427-8971
Sergio BernasconiMicrobiome Research Hub, University of Parma, Via A. Catalani 10, 43123 Parma, Italy.
Azienda Sanitaria Unità Locale di Reggio Emilia · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fetal growth is regulated by a complex interaction of maternal, placental, and fetal factors. The effects and outcomes that chemicals, widely distributed in the environment, may have on the health status of both the mother and the fetus are not yet well defined. Mainly mixtures of chemical substances are found in the mothers and placenta. Exposure to endocrine-disrupting chemicals (EDCs) can be associated with fetal growth retardation, thyroid dysfunction, and neurological disorders. EDCs mostly interfere with insulin, glucocorticoid, estrogenic, and thyroid pathways, with subsequent effects on normal endocrine and metabolic functions, which cause changes in the epigenome and state of inflammation with life-long effects and consequences. International scientific societies recommend the implementation of research and of all possible preventive measures. This review briefly summarizes all these aspects.

Indexed as

Fetal Growth RetardationNervous System DiseasesThyroid DiseasesEndocrine DisruptorsFemaleFetal DevelopmentHumansMaternal ExposurePregnancyEndocrine Disruptorsbirth weightdevelopmental origins of health and disease (DOHAD)endocrine-disrupting chemicals (EDCs)fetal growth restriction (FGR)intrauterine growth restriction (IUGR)placentapostnatal outcomespregnancypreterm birthsmall for gestational age (SGA)

Identifiers

PMID32093249
PMCPMC7073082
OpenAlexW3007925462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.