Evidence map›Paper›PMID 32093216›Full record

ArticleMarine drugs2020

Identification of Quorum Sensing Activators and Inhibitors in The Marine Sponge

Kumar Saurav, Nicola Borbone, Ilia Burgsdorf, Roberta Teta, Alessia Caso, Rinat Bar-Shalom, Germana Esposito, Maya Britstein, Laura Steindler, Valeria Costantino

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Quorum Sensing Inhibition by Sponge-AssociatedAntibiotics (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Kumar SauravDepartment of Marine Biology, Leon H. Charney School of Marine Sciences, University of Haifa, Mt. Carmel 31905, Haifa, Israel.ORCID 0000-0002-7084-4204
Nicola BorboneThe Blue Chemistry Lab, Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131, Napoli, Italy.ORCID 0000-0003-0216-9814
Ilia BurgsdorfDepartment of Marine Biology, Leon H. Charney School of Marine Sciences, University of Haifa, Mt. Carmel 31905, Haifa, Israel.
Roberta TetaThe Blue Chemistry Lab, Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131, Napoli, Italy.
Alessia CasoThe Blue Chemistry Lab, Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131, Napoli, Italy.ORCID 0000-0002-5395-2457
Rinat Bar-ShalomDepartment of Marine Biology, Leon H. Charney School of Marine Sciences, University of Haifa, Mt. Carmel 31905, Haifa, Israel.
Germana EspositoThe Blue Chemistry Lab, Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131, Napoli, Italy.ORCID 0000-0001-9619-7511
Maya BritsteinDepartment of Marine Biology, Leon H. Charney School of Marine Sciences, University of Haifa, Mt. Carmel 31905, Haifa, Israel.
Laura SteindlerDepartment of Marine Biology, Leon H. Charney School of Marine Sciences, University of Haifa, Mt. Carmel 31905, Haifa, Israel.
Valeria CostantinoThe Blue Chemistry Lab, Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131, Napoli, Italy.ORCID 0000-0001-8723-9505
University of Naples Federico II · ITUniversity of Haifa · ILCzech Academy of Sciences · CZ

Funding

Israel Science Foundation 1243/16Planning and Budgeting Committee of the Council for Higher Education of Israel 2015-2018Regione Campania B61G18000470007
6 · The paper itself

Abstract

Marine sponges, a well-documented prolific source of natural products, harbor highly diverse microbial communities. Their extracts were previously shown to contain quorum sensing (QS) signal molecules of the

Indexed as

AnimalsEscherichia coliLuminescent MeasurementsPeptide HydrolasesPhylogenyPoriferaPyocyanineQuorum SensingVirulence FactorsPeptide HydrolasesPyocyanineVirulence Factors3-bromo-4-methoxyphenethylamine5,6-dibromo-N,N-dimethyltryptamineN-acyl homoserine lactonequorum sensingquorum sensing inhibitionSarcotragus spinosulussponge

Identifiers

PMID32093216
PMCPMC7074164
OpenAlexW3008640906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.