ArticlePharmaceutics2020
Halloysite- and Montmorillonite-Loaded Scaffolds as Enhancers of Chronic Wound Healing.
Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Montmorillonite in next-generation drug delivery: patent trends, safety insights, and industrial advancements.Journal of materials science. Materials in medicine · 2026Review
- Smart copper-doped clays in biomimetic microparticles for wound healing and infection control.Materials today. Bio · 2024Article
- Development and characterization of three-dimensional antibacterial nanocomposite sponges of chitosan, silver nanoparticles and halloysite nanotubes.RSC advances · 2024Article
- Nanoclay-Doped Electrospun Nanofibers for Tissue Engineering: Investigation on the Structural Modifications in Physiological Environment.International journal of nanomedicine · 2023Article
- Nanoclays in medicine: a new frontier of an ancient medical practice.Materials advances · 2022Review
- Topographical and Compositional Gradient Tubular Scaffold for Bone to Tendon Interface Regeneration.Pharmaceutics · 2022Article
- Two-dimensional nanovermiculite and polycaprolactone electrospun fibers composite scaffolds promoting diabetic wound healing.Journal of nanobiotechnology · 2022Article
- Inorganic Nanomaterials in Tissue Engineering.Pharmaceutics · 2022Review
- Influence of halloysite nanotubes on the efficiency of Asparaginase against mice Ehrlich solid carcinoma.Saudi journal of biological sciences · 2022Article
- Smart Device for Biologically Enhanced Functional Regeneration of Osteo-Tendon Interface.Pharmaceutics · 2021Article
- Biomaterials for Soft Tissue Repair and Regeneration: A Focus on Italian Research in the Field.Pharmaceutics · 2021Review
- One-Shot Preparation of Polybasic Ternary Hybrid Cryogels Consisting of Halloysite Nanotubes and Tertiary Amine Functional Groups: An Efficient and Convenient Way by Freezing-Induced Gelation.Gels (Basel, Switzerland) · 2021Article
- Electrospun Scaffolds in Periodontal Wound Healing.Polymers · 2021Article
- Clay-Based Pharmaceutical Formulations and Drug Delivery Systems.Pharmaceutics · 2020Article
- Nanotechnology-Based Medical Devices for the Treatment of Chronic Skin Lesions: From Research to the Clinic.Pharmaceutics · 2020Review
- Wound Healing Activity of Nanoclay/Spring Water Hydrogels.Pharmaceutics · 2020Article
- Norfloxacin-Loaded Electrospun Scaffolds: Montmorillonite Nanocomposite vs. Free Drug.Pharmaceutics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
The increase in life expectancy and the increasing prevalence of diabetic disease and venous insufficiency lead to the increase of chronic wounds. The prevalence of ulcers ranges from 1% in the adult population to 3-5% in the over 65 years population, with 3-5.5% of the total healthcare expenditure, as recently estimated. The aim of this work was the design and the development of electrospun scaffolds, entirely based on biopolymers, loaded with montmorillonite (MMT) or halloysite (HNT) and intended for skin reparation and regeneration, as a 3D substrate mimicking the dermal ECM. The scaffolds were manufactured by means of electrospinning and were characterized for their chemico-physical and preclinical properties. The scaffolds proved to possess the capability to enhance fibroblast cells attachment and proliferation with negligible proinflammatory activity. The capability to facilitate the cell adhesion is probably due to their unique 3D structure which are assisting cell homing and would facilitate wound healing in vivo.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.